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公开(公告)号:US20110229465A1
公开(公告)日:2011-09-22
申请号:US13074357
申请日:2011-03-29
申请人: Frank Osterroth , Silke Aigner , Christoph Uherek , Andrea Wartenberg-Demand , Anatoly Rudnev , Michael Soldan , Christoph Bruecher , Benjamin Daelken , Chantal Zuber , Gregor Schulz , Niklas Czeloth
发明人: Frank Osterroth , Silke Aigner , Christoph Uherek , Andrea Wartenberg-Demand , Anatoly Rudnev , Michael Soldan , Christoph Bruecher , Benjamin Daelken , Chantal Zuber , Gregor Schulz , Niklas Czeloth
IPC分类号: A61K39/395 , A61K31/519 , A61K38/13 , A61K31/675 , A61K31/65 , A61K31/575 , A61P19/02 , A61P29/00
CPC分类号: C07K16/2812 , A61K39/39541 , C07K2317/24 , C07K2317/56 , A61K2300/00
摘要: The present invention provides pharmaceutical compositions and kits comprising an agent capable of activating CD4+CD25+ regulatory T cells and methotrexate, and methods of treatment and medical uses utilising the same.
摘要翻译: 本发明提供了包含能够激活CD4 + CD25 +调节性T细胞和甲氨蝶呤的药剂的药物组合物和试剂盒,以及利用其的治疗方法和医疗用途。