摘要:
Acetic acid derivatives of the formula: ##STR1## and pharmaceutically acceptable alkali metal salts thereof, wherein R represents the radical ##STR2## in which R.sub.1 and R.sub.2, which may be the same or different, each represent an alkyl radical having from 1 to 4 carbon atoms, R.sub.3 represents a hydrogen atom or a methyl radical and n is an integer in the range of from 0 to 3 inclusive.They possess a competitive inhibitory activity with respect to .gamma.-aminobutyric .alpha.-ketoglutaric transaminase as well as antianoxic and anticonvulsant properties and they are useful for treating central neurological disorders whether resulting or not from cerebral ischemia.
摘要:
Acetoxime derivatives of formula: ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3, which may be the same or different, each represent a branched- or straight-chain alkyl radical having from 1 to 4 carbon atoms or R.sub.1 and R.sub.2, when they are taken together, represent with the carbon atom to which they are attached, a cyclohexyl group, are useful for treating disturbances of the mental functions including anxiety and as anticonvulsants.