公开(公告)号：US20060153832A1

公开(公告)日：2006-07-13

申请号：US11385111

申请日：2006-03-21

申请人： Arthur Tzianabos ,  Dennis Kasper ,  Andrew Onderdonk ,  Ying Wang

发明人： Arthur Tzianabos ,  Dennis Kasper ,  Andrew Onderdonk ,  Ying Wang

IPC分类号： A61K39/395

CPC分类号： A61K31/715 ,  A61K31/785 ,  A61K35/742 ,  A61K38/00 ,  A61K45/06

摘要： Methods and products for inducing IL-2 secretion, inducing IL-10 secretion, activating T cells, suppressing IgG antibody response to specific antigen, promoting allograft survival, reducing postoperative surgical adhesion formation, and protecting against abscess formation associated with surgery, trauma or diseases that predispose the host to abscess formation are provided. The methods of the invention are accomplished using an immunomodulator which is a polymer having at least two repeating charge motifs separated by at least a certain minimum distance.

公开(公告)号：US20060029662A1

公开(公告)日：2006-02-09

申请号：US11176701

申请日：2005-07-07

申请人： Pericles Calias ,  Robert Miller ,  Andrew Onderdonk ,  Arthur Tzianabos

发明人： Pericles Calias ,  Robert Miller ,  Andrew Onderdonk ,  Arthur Tzianabos

IPC分类号： A61K9/54 ,  A61K31/17

CPC分类号： A61K45/06 ,  A61K31/17 ,  A61K31/265 ,  A61K31/452 ,  A61K31/5375 ,  Y02A50/402 ,  Y02A50/473 ,  Y10S514/825

摘要： The invention relates to immunomodulatory compositions and related methods. The immunomodulatory compositions of a formula disclosed herein are useful for the prevention of sepsis and the treatment and prevention of diseases associated with inflammation and/or NOS.

摘要翻译： 本发明涉及免疫调节组合物和相关方法。 本文公开的式的免疫调节组合物可用于预防败血症和治疗和预防与炎症和/或NOS相关的疾病。