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1.发明申请N-(4-(4-methylthiazol-5-yl) pyrimidin-2-yl)-N-phenylamines as antiproliferative compounds 有权N-（4-（4-甲基噻唑-5-基）嘧啶-2-基）-N-苯胺作为抗增殖化合物公开(公告)号：US20060199830A1
公开(公告)日：2006-09-07
申请号：US11433312
申请日：2006-05-11
IPC分类号： A61K31/505 , C07D417/02
CPC分类号： C07D417/04
摘要： The present invention relates to 2-substituted 4-heteroaryl-pyrimidines, their preparation, pharmaceutical compositions containing them and their use as inhibitors of cyclin-dependent kinases (CDKs) and hence their use in the treatment of proliferative disorders such as cancer, leukaemia, psoriasis and the like.
摘要翻译： 本发明涉及2-取代的4-杂芳基嘧啶，其制备方法，含有它们的药物组合物及其作为细胞周期蛋白依赖性激酶（CDK）抑制剂的用途，因此可用于治疗增殖性疾病如癌症，白血病， 牛皮癣等。
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2.发明授权N-(4-(4-methylthiazol-5-yl) pyrimidin-2-yl)-N-phenylamines as antiproliferative compounds 有权N-（4-（4-甲基噻唑-5-基）嘧啶-2-基）-N-苯胺作为抗增殖化合物公开(公告)号：US07427627B2
公开(公告)日：2008-09-23
申请号：US11433312
申请日：2006-05-11
IPC分类号： C07D417/04 , A61K31/506
CPC分类号： C07D417/04
摘要： The present invention relates to 2-substituted 4-heteroaryl-pyrimidines, their preparation, pharmaceutical compositions containing them and their use as inhibitors of cyclin-dependent kinases (CDKs) and hence their use in the treatment of proliferative disorders such as cancer, leukaemia, psoriasis and the like.
摘要翻译： 本发明涉及2-取代的4-杂芳基嘧啶，其制备方法，含有它们的药物组合物及其作为细胞周期蛋白依赖性激酶（CDK）抑制剂的用途，因此可用于治疗增殖性疾病如癌症，白血病， 牛皮癣等。
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3.发明授权N-(4-(4-methylthiazol-5-yl)pyrimidin-2-yl)-N-phenylamines as antiproliferative compounds 有权N-（4-（4-甲基噻唑-5-基）嘧啶-2-基）-N-苯胺作为抗增殖化合物公开(公告)号：US07388015B2
公开(公告)日：2008-06-17
申请号：US10810767
申请日：2004-03-26
IPC分类号： C07D417/04 , A61K31/506
CPC分类号： C07D417/04
摘要： The present invention relates to 2-substituted 4-heteroaryl-pyrimidines, their preparation, pharmaceutical compositions containing them and their use as inhibitors of cyclin-dependent kinases (CDKs) and hence their use in the treatment of proliferative disorders such as cancer, leukaemia, psoriasis and the like.
摘要翻译： 本发明涉及2-取代的4-杂芳基嘧啶，其制备方法，含有它们的药物组合物及其作为细胞周期蛋白依赖性激酶（CDK）抑制剂的用途，因此可用于治疗增殖性疾病如癌症，白血病， 牛皮癣等。
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