公开(公告)号：US5198221A

公开(公告)日：1993-03-30

申请号：US835014

申请日：1992-02-12

申请人： Andrew R. Clark ,  Anne M. Hollingworth

发明人： Andrew R. Clark ,  Anne M. Hollingworth

IPC分类号： A61K9/00 ,  A61K31/47

CPC分类号： A61K9/0075 ,  A61K31/47

摘要： Particulate nedocromil sodium with a mass median diameter of from 5 to 10 .mu.m is useful as a medicament for inhalation.The particulate nedocromil sodium of the invention is particularly advantageous in that its dispersion, i.e. the proportion of particles which are capable of penetrating deep into the lung, is substantially greater than the dispersion of conventional powders having smaller mass median diameters.

摘要翻译： 质量中值粒径为5至10微米的粒状奈多罗米钠可用作吸入药物。 本发明的颗粒尼多菌素钠是特别有利的，因为其分散体，即能够深入肺的颗粒的比例基本上大于具有较小质量中值直径的常规粉末的分散体。

公开(公告)号：US5356631A

公开(公告)日：1994-10-18

申请号：US10480

申请日：1993-01-28

申请人： Andrew R. Clark ,  Anne M. Hollingworth

发明人： Andrew R. Clark ,  Anne M. Hollingworth

IPC分类号： A61K9/00 ,  A61K31/47 ,  A23K1/18

CPC分类号： A61K9/0075 ,  A61K31/47

摘要： Particulate nedocromil sodium with a mass median diameter of from 5 to 10 .mu.m is useful as a medicament for inhalation.The particulate nedocromil sodium of the invention is particularly advantageous in that its dispersion, i.e. the proportion of particles which are capable of penetrating deep into the lung, is substantially greater than the dispersion of conventional powders having smaller mass median diameters.

摘要翻译： 质量中值粒径为5至10微米的粒状奈多罗米钠可用作吸入药物。 本发明的颗粒尼多菌素钠是特别有利的，因为其分散体，即能够深入肺的颗粒的比例基本上大于具有较小质量中值直径的常规粉末的分散体。