专利检索 ap:"Anthony Pechulis" 第 1 页

1.

发明申请
Novel 4-phenyl substituted tetrahydroisoquinolines and therapeutic use thereof 失效
标题翻译：新型4-苯基取代的四氢异喹啉及其治疗用途

公开(公告)号：US20060217409A1

公开(公告)日：2006-09-28

申请号：US11438725

申请日：2006-05-22

申请人： James Beck , Anthony Pechulis , Arthur Harms

发明人： James Beck , Anthony Pechulis , Arthur Harms

IPC分类号： A61K31/4743 , C07D498/02

CPC分类号： C07D491/04 , C07D493/04 , C07D495/04

摘要： Compounds are provided that, by way of their selective neurotransmitter binding useful for the treatment of various neurological and psychological disorders, e.g., ADHD. Such compounds are 4-phenyl substituted tetrahydroisoquinolines having the Formula IA, IB, IIA, IIB, IIIA or IIIC as set forth herein.

摘要翻译： 提供化合物，其通过其可用于治疗各种神经和心理障碍（例如ADHD）的选择性神经递质结合。这样的化合物是如本文所述的具有式IA，IB，IIA，IIB，IIIA或IIIC的4-苯基取代的四氢异喹啉。

2.

发明授权
Heteroaromatic substituted cyclopropane as corticotropin releasing hormone ligands 有权
标题翻译：杂环取代环丙烷作为促肾上腺皮质激素释放激素配体

公开(公告)号：US07297708B2

公开(公告)日：2007-11-20

申请号：US10235436

申请日：2002-09-05

申请人： Andreas Termin , Peter D. J. Grootenhuis , Dean M. Wilson , Valentina Molteni , Long Mao , Angelo Castellino , Zhicai Yang , Anthony Pechulis , Mark Suto

发明人： Andreas Termin , Peter D. J. Grootenhuis , Dean M. Wilson , Valentina Molteni , Long Mao , Angelo Castellino , Zhicai Yang , Anthony Pechulis , Mark Suto

IPC分类号： A61K31/4164 , C07D233/54

CPC分类号： C07D213/30 , C07D233/64 , C07D239/26 , C07D241/12 , C07D249/08

摘要： Provided herein are novel heteroaromatic substituted cyclopropanes of the Formula (I): as well as compositions, including pharmaceutical compositions, containing the same, and the use thereof in the treatment of various neurological and psychological disorders, e.g., anxiety and depression, treatable by antagonizing CRF receptors.

摘要翻译： 本文提供了式（I）的新型杂芳族取代的环丙烷：以及包含其的组合物，包括药物组合物，以及其用于治疗各种神经和心理障碍，例如焦虑和抑郁症的用途，可通过拮抗 CRF受体。

3.

发明申请
Novel 4-phenyl substituted tetrahydroisoquinolines and therapeutic use thereof 失效

公开(公告)号：US20060025435A1

公开(公告)日：2006-02-02

申请号：US11231398

申请日：2005-09-21

申请人： James Beck , Anthony Pechulis , Arthur Harms

发明人： James Beck , Anthony Pechulis , Arthur Harms

IPC分类号： A61K31/4745 , A61K31/47

CPC分类号： C07D491/04 , C07D493/04 , C07D495/04

摘要： Compounds are provided that, by way of their selective neurotransmitter binding useful for the treatment of various neurological and psychological disorders, e.g., ADHD. Such compounds are 4-phenyl substituted tetrahydroisoquinolines having the Formula IA, IB, IIA, IIB, IIIA or IIIC as set forth herein.