Frequency generator for NMR applications with direct digital frequency synthesis (DDS)

    公开(公告)号:US06411093B1

    公开(公告)日:2002-06-25

    申请号:US09780406

    申请日:2001-02-12

    IPC分类号: G01V300

    摘要: A method of operating a high-resolution NMR spectrometer comprising a DDS generator containing an NCOL for generating an LO frequency, wherein the frequency of the NCOL is defined by inputting a numerical value Z, is characterized in that this numerical value Z may assume only values which satisfy the equation Z=n·N/m, wherein Z, n, N, and m are integer and positive numbers, N is a power of 2 with a positive integer exponent, wherein said exponent represents the maximum number of bits during the calculation process, m is approximately 2·fs/&Dgr;B, n approximately m·fout/fs and m additionally a common integer divisor of n·N and fs is the clock frequency of the NCOL, &Dgr;B is the desired bandwidth with high spectral purity and fout is the output frequency of the NCOL. This method allows the use of a DDS generator even in the case where very high spectral purity is required, wherein in particular quantization noise is largely eliminated over the frequency range relevant for NMR measurements.

    Device for highly precise synchronization of the NMR transmission frequency to the resonance frequency of an NMR line while taking into consideration a non-constant RF phase
    3.
    发明申请
    Device for highly precise synchronization of the NMR transmission frequency to the resonance frequency of an NMR line while taking into consideration a non-constant RF phase 有权
    用于在考虑非恒定RF相位时将NMR传输频率与NMR谱线的谐振频率进行高精度同步的装置

    公开(公告)号:US20100271025A1

    公开(公告)日:2010-10-28

    申请号:US12662388

    申请日:2010-04-14

    IPC分类号: G01R33/48

    摘要: A device that comprises an RF generator (29), an NMR transmission (20) and reception system (21) and a first control loop (28), with which the frequency fRF of the RF generator is synchronized with the resonance frequency f0 of an NMR line, wherein, from the signal of the RF generator, a train of excitation pulses (EX) of the repetition frequency fm is generated, with which nuclear spins of a certain resonance frequency of an associated NMR line are excited quasi-continuously (CW) and, in the times between the excitation pulses, the NMR signal is received (AQ), wherein the period time 1/fm is chosen to be much smaller than the relaxation time of the NMR line, preferably shorter than 1/10 of the relaxation time, and the NMR signal UD mixed down into the low-frequency range is used, with the help of the first control loop, to closed-loop-control the value of the transmission frequency (=frequency lock) or the value of the B0 field (=field lock) in such a way that the frequency and phase of the RF generator and the NMR line match as precisely as possible, characterized in that a phase shifter (22) that rotates the radio-frequency phase of the NMR transmission and reception system in the first control loop by the value Δφ is controlled by a second control loop (27) whose input signal comes from a signal extraction stage (25, 26) that extracts the saw-tooth AC component of the signal UD and maintains this input signal at zero by closed-loop control. In this way, the influence of the RF phase on the synchronization process can be taken into consideration to improve the precision with which the resonance frequency of an NMR line is synchronized.

    摘要翻译: 一种包括RF发生器(29),NMR传输(20)和接收系统(21)以及第一控制环路(28)的装置,RF发生器的频率fRF与RF发生器的谐振频率f0同步 NMR线,其中,根据RF发生器的信号,产生一系列重复频率f m的激励脉冲(EX),与之相关联的NMR线的某个共振频率的核自旋被准星激励(CW ),并且在激发脉冲之间的时间内接收NMR信号(AQ),其中周期时间1 / fm被选择为远小于NMR线的弛豫时间,优选短于NMR线的1/10 松弛时间和混合到低频范围内的NMR信号UD,在第一个控制环路的帮助下,使用闭环控制传输频率(=频率锁定)的值或 B0字段(=字段锁)以这样的方式使频率和相位 射频发生器和NMR线路尽可能精确地匹配,其特征在于:使所述第一控制回路中的所述NMR发射和接收系统的射频相位旋转的移相器(22)的值&Dgr; 由第二控制回路(27)控制,其输入信号来自提取信号UD的锯齿AC分量的信号提取级(25,26),并通过闭环控制将该输入信号保持在零。 以这种方式,可以考虑RF相对同步过程的影响,以提高NMR线的共振频率同步的精度。

    Passively damped magnetic resonance (MR) detection configuration
    4.
    发明授权
    Passively damped magnetic resonance (MR) detection configuration 有权
    被动阻尼磁共振(MR)检测配置

    公开(公告)号:US07723988B2

    公开(公告)日:2010-05-25

    申请号:US11882150

    申请日:2007-07-31

    IPC分类号: G01V3/00

    摘要: A magnetic resonance (MR) detection configuration comprising at least one RF resonant circuit with an inductance, a preamplifier module and an RF receiver, wherein a reactive transformation circuit is connected between a high-impedance point of the inductance and a low-impedance connecting point of the RF resonant circuit, which acts as an impedance transformer and wherein the low-impedance connecting point is connected to the preamplifier module via an RF line having a characteristic impedance, is characterized in that at least one passive damping impedance is provided in the preamplifier module downstream of the RF line, wherein the passive damping impedance can be connected to the resonant circuit by a switching means during a damping and/or transmitting process, and wherein the respective amount of the complex reflection factor of passive damping impedance relative to the characteristic impedance of the RF line exceeds a value of 0.5. This presents an MR detection configuration with an extensive damping concept, wherein all three processes (transmitting, damping and receiving processes) are optimized.

    摘要翻译: 一种磁共振(MR)检测配置,其包括至少一个具有电感的RF谐振电路,前置放大器模块和RF接收器,其中无功变换电路连接在电感的高阻点与低阻抗连接点 的RF谐振电路,其作为阻抗变换器,并且其中低阻抗连接点经由具有特征阻抗的RF线连接到前置放大器模块,其特征在于,在前置放大器中提供至少一个被动阻尼阻抗 在所述RF线路的下游模块,其中所述无源阻尼阻抗可以在阻尼和/或发射过程期间通过开关装置连接到所述谐振电路,并且其中相对于所述特性的无源阻尼阻抗的复反射系数的相应量 RF线的阻抗超过0.5。 这提出了具有广泛的阻尼概念的MR检测配置,其中所有三个过程(发射,阻尼和接收过程)被优化。

    Passively damped magnetic resonance (MR) detection configuration
    5.
    发明申请
    Passively damped magnetic resonance (MR) detection configuration 有权
    被动阻尼磁共振(MR)检测配置

    公开(公告)号:US20080061783A1

    公开(公告)日:2008-03-13

    申请号:US11882150

    申请日:2007-07-31

    IPC分类号: G01V3/00

    摘要: A magnetic resonance (MR) detection configuration comprising at least one RF resonant circuit (1) with an inductance (L), a preamplifier module (2) and an RF receiver (7), wherein a reactive transformation circuit is connected between a high-impedance point (M) of the inductance (L) and a low-impedance connecting point (A) of the RF resonant circuit (1), which acts as an impedance transformer and wherein the low-impedance connecting point (A) is connected to the preamplifier module (2) via an RF line (15) having a characteristic impedance RW), is characterized in that at least one passive damping impedance (ZDV, ZSV, ZDV′, ZSV′) is provided in the preamplifier module (2) downstream of the RF line (15), wherein the passive damping impedance (ZDV, ZSV, ZDV′, ZSV′) can be connected to the resonant circuit (1) by a switching means during a damping and/or transmitting process, and wherein the respective amount of the complex reflection factor of passive damping impedance (ZDV, ZSV, ZDV′, ZSV′) relative to the characteristic impedance RW) of the RF line (15) exceeds a value of 0.5. This presents an MR detection configuration with an extensive damping concept, wherein all three processes (transmitting, damping and receiving processes) are optimized.

    摘要翻译: 一种包括具有电感(L)的至少一个RF谐振电路(1),前置放大器模块(2)和RF接收器(7))的磁共振(MR)检测配置,其中, 作为阻抗变换器的RF谐振电路(1)的电感(L)的阻抗点(M)和低阻抗连接点(A),其中低阻抗连接点(A)连接到 前置放大器模块(2)经由具有特征阻抗R W W的RF线路(15))的特征在于,至少一个被动阻尼阻抗(Z Z DV,Z 在RF线路(15)的下游的前置放大器模块(2)中提供有SV SV,Z SV,Z SV, 可以连接被动阻尼阻抗(Z DV DV>,>>>,,Z Z Z,,,,,,connected connected connected connected connected connected connected connected connected connected connected>>>>>>>>>>>>>>>>> 在阻尼和/或发送过程中通过开关装置耦合到谐振电路(1) ,并且其中无源阻尼阻抗(Z N DV,Z SV),Z V DV',Z W>的相位> SV'<>>超过0.5的值。 这提出了具有广泛的阻尼概念的MR检测配置,其中所有三个过程(发射,阻尼和接收过程)被优化。

    Method and device for compensating of field disturbances in magnetic
fields
    6.
    发明授权
    Method and device for compensating of field disturbances in magnetic fields 失效
    用于补偿磁场中的场干扰的方法和装置

    公开(公告)号:US5302899A

    公开(公告)日:1994-04-12

    申请号:US910661

    申请日:1992-07-07

    IPC分类号: G01R33/24 G01R33/389 G01V3/00

    CPC分类号: G01R33/24 G01R33/389

    摘要: In a method for compensation of time variant field disturbances in magnetic fields of electromagnets with high field-homogeneity, in particular in sample volumes of superconducting electromagnets for measurements of magnetic resonance, the dispersion signal u.sub.x of the nuclear signal of a reference substance is acquired and taken into consideration for compensation by generation of a current dependent on the dispersion signal in a field correction coil of the electromagnet. The method is characterized in that the absorption signal u.sub.y of the reference substance is additionally acquired and that the compensation is carried out in dependence on the quantity u.sub.x /u.sub.y and/or (1/u.sub.y)(du.sub.x /dt). These are substantially independent of many influencing quantities.

    摘要翻译: 在用于补偿具有高场均匀性的电磁体的磁场中的时变场扰动的方法中,特别是用于测量磁共振的超导电磁体的采样体积中,获取参考物质的核信号的色散信号ux, 考虑到通过在电磁体的场校正线圈中产生依赖于色散信号的电流进行补偿。 该方法的特征在于另外获取参考物质的吸收信号uy,并且根据ux / uy和/或(1 / uy)(dux / dt)的量进行补偿。 这些基本上与许多影响量无关。