公开(公告)号：US07371324B2

公开(公告)日：2008-05-13

申请号：US10332107

申请日：2001-06-14

申请人： Raymond Vincent Heavon Jones ,  Joanne Emma Murray ,  Jennifer Ann White ,  Barry Stuart Crombie ,  James Samuel Shane Rountree ,  Jacqueline Ann Campbell

发明人： Raymond Vincent Heavon Jones ,  Joanne Emma Murray ,  Jennifer Ann White ,  Barry Stuart Crombie ,  James Samuel Shane Rountree ,  Jacqueline Ann Campbell

IPC分类号： B01D11/00

CPC分类号： C02F1/26 ,  C02F2101/34 ,  Y10S210/909

摘要： A process for extracting from aqueous solution the alkali metal or ammonium salt of a phenol, naphthol, anthrol or phenanthrol or the corresponding thiol, which comprises contacting an aqueous alkaline or neutral solution of the alkali metal or ammonium salt, in which is dissolved an alkali metal or ammonium fluoride, chloride, bromide, hydroxide, nitrate, nitrite, sulphate, sulphite, sulphide, thiosulphate, phosphate, hydrogen phosphate, carbonate, bicarbonate, cyanate, cyanide, thiocyanate, borate, chlorate, chlorite, hypochlorite, perchlorate, chromate, dichromate or permanganate, with a partially water-miscible organic solvent so as to transfer aqueous solution of the alkali metal or ammonium salt of the phenol, naphthol, anthrol or phenanthrol or corresponding thiol into the solvent while retaining separate aqueous and solvent phases, and thereafter separating the solvent phase containing the alkali metal or ammonium salt and water from the aqueous phase, the ratio of solvent to water in the separated solvent phase being from 0.5:1 to 10:1 w/w.

摘要翻译： 从水溶液中提取苯酚，萘酚，蒽或菲或其相应的硫醇的碱金属盐或铵盐的方法，该方法包括将碱金属盐或铵盐的碱性或中性水溶液与碱溶解的碱 硝酸盐，硫酸盐，硫酸盐，硫酸盐，硫酸盐，磷酸盐，磷酸盐，碳酸盐，碳酸氢盐，氰酸盐，氰化物，硫氰酸盐，硼酸盐，氯酸盐，亚氯酸盐，次氯酸盐，高氯酸盐，铬酸盐， 重铬酸盐或高锰酸盐，与部分水混溶的有机溶剂，以便将苯酚，萘酚，蒽酮或菲或菲硫醇的碱金属盐或铵盐的水溶液转移到溶剂中，同时保持分开的水相和溶剂相，之后 从水相中分离含有碱金属或铵盐和水的溶剂相，溶剂与w的比例 在分离的溶剂相中的比例为0.5:1至10:1w / w。

公开(公告)号：US6096892A

公开(公告)日：2000-08-01

申请号：US191491

申请日：1998-11-13

申请人： Barry Stuart Crombie ,  David John Ritchie ,  Raymond Vincent Heavon Jones

发明人： Barry Stuart Crombie ,  David John Ritchie ,  Raymond Vincent Heavon Jones

IPC分类号： C07D239/54 ,  C07D239/52

CPC分类号： C07D239/54

摘要： A process for preparing 4,6-dihydroxypyrimidine comprising the steps:a) contacting formamide, an alkoxide of formula ROM and a malonate of formula CH.sub.2 (CO.sub.2 R).sub.2 in a solvent of formula ROH;b) adding water to the product of step (a);c) removing substantially all of the solvent of formula ROH from the product of step (b); andd) acidifying the product of step (c)wherein R is C.sub.1-4 alkyl and M is an alkali metal.

摘要翻译： 制备4,6-二羟基嘧啶的方法，包括以下步骤：a）在式ROH的溶剂中将甲酰胺，式ROM的醇盐和式CH 2（CO 2 R）2的丙二酸酯接触） b）向步骤（a）的产物中加入水; c）从步骤（b）的产物中基本上除去所有式ROH的溶剂; 和d）酸化步骤（c）的产物，其中R是C 1-4烷基，M是碱金属。