COMPOSITIONS AND METHODS FOR THERAPY FOR DISEASES CHARACTERIZED BY DEFECTIVE CHLORIDE TRANSPORT
    1.
    发明申请
    COMPOSITIONS AND METHODS FOR THERAPY FOR DISEASES CHARACTERIZED BY DEFECTIVE CHLORIDE TRANSPORT 失效
    缺陷氯化物运输特征的疾病治疗组合物和方法

    公开(公告)号:US20100286256A1

    公开(公告)日:2010-11-11

    申请号:US12722136

    申请日:2010-03-11

    IPC分类号: A61K31/352 A61K31/12 A61P1/12

    摘要: Compositions and methods for therapy of cystic fibrosis, asthma, and other conditions characterized by defective chloride transport are provided. The compositions comprise one or more compounds such as flavones and/or isoflavones, ascorbate and/or derivatives thereof capable of stimulating chloride transport in epithelial tissues. Therapeutic methods involve the administration (e.g., orally or via inhalation) of such compositions to a patient afflicted with cystic fibrosis, asthma, and/or another condition responsive to stimulation of chloride transport.

    摘要翻译: 提供了用于治疗囊性纤维化,哮喘和以氯化物运输有缺陷为特征的其它病症的组合物和方法。 组合物包含一种或多种化合物,例如能够刺激上皮组织中的氯化物转运的黄酮和/或异黄酮,抗坏血酸和/或其衍生物。 治疗方法包括将这种组合物给予(例如口服或经吸入)给患有囊性纤维化,哮喘和/或响应于氯化物转运刺激的另一种病症的患者。

    Compositions and methods for therapy for diseases characterized by defective chloride transport
    3.
    发明授权
    Compositions and methods for therapy for diseases characterized by defective chloride transport 有权
    用于治疗以氯化物运输不良为特征的疾病的组合物和方法

    公开(公告)号:US07718694B2

    公开(公告)日:2010-05-18

    申请号:US10769619

    申请日:2004-01-30

    IPC分类号: A61K31/35 A61K31/21

    摘要: Compositions and methods for therapy of cystic fibrosis, asthma, and other conditions characterized by defective chloride transport are provided. The compositions comprise one or more compounds such as flavones and/or isoflavones, ascorbate and/or derivatives thereof capable of stimulating chloride transport in epithelial tissues. Therapeutic methods involve the administration (e.g., orally or via inhalation) of such compositions to a patient afflicted with cystic fibrosis, asthma, and/or another condition responsive to stimulation of chloride transport.

    摘要翻译: 提供了用于治疗囊性纤维化,哮喘和以氯化物运输有缺陷为特征的其它病症的组合物和方法。 组合物包含一种或多种化合物,例如能够刺激上皮组织中的氯化物转运的黄酮和/或异黄酮,抗坏血酸和/或其衍生物。 治疗方法包括将这种组合物给予(例如口服或经吸入)给患有囊性纤维化,哮喘和/或响应于氯化物转运刺激的另一种病症的患者。

    Compositions and methods for cystic fibrosis therapy
    4.
    发明授权
    Compositions and methods for cystic fibrosis therapy 有权
    囊性纤维化治疗的组合和方法

    公开(公告)号:US06329422B1

    公开(公告)日:2001-12-11

    申请号:US09174077

    申请日:1998-10-16

    IPC分类号: A61K3135

    摘要: Compositions and methods for therapy of cystic fibrosis and other conditions are provided. The compositions comprise one or more compounds such as flavones and/or isoflavones capable of stimulating chloride transport in epithelial tissues. Therapeutic methods involve the administration (e.g., orally or via inhalation) of such compositions to a patient afflicted with cystic fibrosis and/or another condition responsive to stimulation of chloride transport.

    摘要翻译: 提供了治疗囊性纤维化和其他病症的组合物和方法。 组合物包含一种或多种化合物,例如能够刺激上皮组织中的氯转运的黄酮和/或异黄酮。 治疗方法包括将这种组合物施用(例如口服或通过吸入)给患有囊性纤维化的患者和/或响应于氯化物转运刺激的另一种病症。

    Compositions and methods for therapy for diseases characterized by defective chloride transport
    5.
    发明授权
    Compositions and methods for therapy for diseases characterized by defective chloride transport 失效
    用于治疗以氯化物运输不良为特征的疾病的组合物和方法

    公开(公告)号:US08138158B2

    公开(公告)日:2012-03-20

    申请号:US12722136

    申请日:2010-03-11

    IPC分类号: A61K31/70 A01N43/04

    摘要: Compositions and methods for therapy of cystic fibrosis, asthma, and other conditions characterized by defective chloride transport are provided. The compositions comprise one or more compounds such as flavones and/or isoflavones, ascorbate and/or derivatives thereof capable of stimulating chloride transport in epithelial tissues. Therapeutic methods involve the administration (e.g., orally or via inhalation) of such compositions to a patient afflicted with cystic fibrosis, asthma, and/or another condition responsive to stimulation of chloride transport.

    摘要翻译: 提供了用于治疗囊性纤维化,哮喘和以氯化物运输有缺陷为特征的其它病症的组合物和方法。 组合物包含一种或多种化合物,例如能够刺激上皮组织中的氯化物转运的黄酮和/或异黄酮,抗坏血酸和/或其衍生物。 治疗方法包括将这种组合物给予(例如口服或经吸入)给患有囊性纤维化,哮喘和/或响应于氯化物转运刺激的另一种病症的患者。

    Compositions and methods for cystic fibrosis therapy
    6.
    发明授权
    Compositions and methods for cystic fibrosis therapy 有权
    囊性纤维化治疗的组合和方法

    公开(公告)号:US07335683B2

    公开(公告)日:2008-02-26

    申请号:US09982315

    申请日:2001-10-17

    摘要: Compositions and methods for therapy of cystic fibrosis and other conditions are provided. The compositions comprise one or more compounds such as flavones and/or isoflavones capable of stimulating chloride transport in epithelial tissues. Therapeutic methods involve the administration (e.g., orally or via inhalation) of such compositions to a patient afflicted with cystic fibrosis and/or another condition responsive to stimulation of chloride transport.

    摘要翻译: 提供了治疗囊性纤维化和其他病症的组合物和方法。 组合物包含一种或多种化合物,例如能够刺激上皮组织中的氯转运的黄酮和/或异黄酮。 治疗方法包括将这种组合物施用(例如口服或通过吸入)给患有囊性纤维化的患者和/或响应于氯化物转运刺激的另一种病症。