公开(公告)号：US06984387B1

公开(公告)日：2006-01-10

申请号：US09254966

申请日：1997-09-08

申请人： Roberto Correa ,  Hans-Robert Hehnen ,  Eberhard Pfaff ,  Armin Saalmüller ,  Thomas Pauly ,  Bettina Höhlich ,  Bernadette Glatthaar-Saalmüller ,  Karl-Heinz Wiesmüller

发明人： Roberto Correa ,  Hans-Robert Hehnen ,  Eberhard Pfaff ,  Armin Saalmüller ,  Thomas Pauly ,  Bettina Höhlich ,  Bernadette Glatthaar-Saalmüller ,  Karl-Heinz Wiesmüller

IPC分类号： A61K39/125

CPC分类号： C07K14/005 ,  A61K39/00 ,  C12N2770/32122 ,  C12N2770/32134

摘要： The present invention relates to FMDC vaccine based on peptides having a sequence of at least 8 amino acids, which corresponds to a partial sequence of the non-structural protein region of FMDV, which was selected by immunoreactivity with FMDV-specific antibodies or by immunoreactivity with FMDV-specific T lymphocytes, and to their production and their use.

摘要翻译： 本发明涉及基于具有至少8个氨基酸序列的肽的FMDC疫苗，其对应于FMDV的非结构蛋白质区域的部分序列，其通过与FMDV特异性抗体的免疫反应性或通过与FMDV特异性抗体的免疫反应性来选择， FMDV特异性T淋巴细胞，以及其生产和使用。