公开(公告)号：US20100104518A1

公开(公告)日：2010-04-29

申请号：US12444680

申请日：2007-01-16

申请人： Jianwei J. Cai ,  Minmin Tian ,  Michael J. Greenberg ,  Scott W. Marske ,  Biao Che ,  Albert H. Chapdelaine ,  Zheng Xia Han ,  Wen Xiong Huang

发明人： Jianwei J. Cai ,  Minmin Tian ,  Michael J. Greenberg ,  Scott W. Marske ,  Biao Che ,  Albert H. Chapdelaine ,  Zheng Xia Han ,  Wen Xiong Huang

IPC分类号： A61K9/68

CPC分类号： A61K9/0058 ,  A23G4/06 ,  A23G4/062 ,  A23G4/068 ,  A23G4/20

摘要： A method for producing a chewing gum with a controlled release traditional Chinese medicine active agent, as well as the chewing gum so produced, is obtained by physically modifying the release properties of the traditional Chinese medicine active agent by coating and drying. The traditional Chinese medicine active agent is coated by encapsulation, partially coated by agglomeration, entrapped by absorption, or treated by multiple steps of encapsulation, agglomeration, and absorption. The coated traditional Chinese medicine active agent is preferably then co-dried and particle sized to produce a release-modified traditional Chinese medicine active agent for use in chewing gum. The traditional Chinese medicine active agent may also be used in a coating on a chewing gum product, as part of a rolling compound applied to the chewing gum product, or as a part of the liquid in a liquid-center chewing gum product.

摘要翻译： 通过涂覆和干燥物理改变中药活性剂的释放性能，获得了具有控制释放中药活性剂的口香糖以及所生产的口香糖的方法。 中药活性剂通过包封进行包衣，通过附聚部分包被，通过吸收包埋，或通过包封，附聚和吸收的多个步骤进行处理。 然后优选涂敷的中药活性剂，同时干燥并调整颗粒大小以产生用于口香糖的释放改性的中药活性剂。 中草药活性剂也可以用作口香糖产品上的涂层，作为应用于口香糖产品的滚动化合物的一部分，或作为液体中心口香糖产品中的液体的一部分使用。