公开(公告)号：US20210324473A1

公开(公告)日：2021-10-21

申请号：US17204898

申请日：2021-03-17

申请人： Biome Health, Inc.

发明人： Alain MIR ,  Harris SHAPIRO ,  Ronald Avignone ,  Mark Kelleher

IPC分类号： C12Q1/6883 ,  G16B35/20 ,  G16B30/00 ,  G16H10/40 ,  G16B40/00 ,  G16B10/00 ,  G16H20/60 ,  C12Q1/6888 ,  G16H50/30

摘要： Provided herein are methods for altering a health state of a subject by administering a wellness intervention to subjects found to have quantitative measures of microbial genera in the subject's microbiome that are associated with undesirable health states. Undesirable health states can be inferred by executing models that predict health states based on the quantitative measures, such as relative amounts of selected microbial genera to all microbes. Models are created by statistical methods that analyze datasets that include, for each of a plurality of subjects, verified health states and quantitative measures of each of a plurality of microbes classified at designated taxonomic levels, e.g., genus level.

公开(公告)号：US20200270699A1

公开(公告)日：2020-08-27

申请号：US16852534

申请日：2020-04-19

申请人： Biome Health, Inc.

发明人： Alain MIR ,  Harris SHAPIRO ,  Ronald Avignone ,  Mark Kelleher

IPC分类号： C12Q1/6883 ,  G16B35/20 ,  G16B30/00 ,  C12Q1/6888 ,  G16B40/00 ,  G16B10/00 ,  G16H20/60 ,  G16H10/40

摘要： Provided herein are methods for altering a health state of a subject by administering a wellness intervention to subjects found to have quantitative measures of microbial genera in the subject's microbiome that are associated with undesirable health states. Undesirable health states can be inferred by executing models that predict health states based on the quantitative measures, such as relative amounts of selected microbial genera to all microbes. Models are created by statistical methods that analyze datasets that include, for each of a plurality of subjects, verified health states and quantitative measures of each of a plurality of microbes classified at designated taxonomic levels, e.g., genus level.

公开(公告)号：US10982283B2

公开(公告)日：2021-04-20

申请号：US16852534

申请日：2020-04-19

申请人： Biome Health, Inc.

发明人： Alain Mir ,  Harris Shapiro ,  Ronald Avignone ,  Mark Kelleher

IPC分类号： C12Q1/6883 ,  G16B35/20 ,  G16B30/00 ,  G16H10/40 ,  G16B40/00 ,  G16B10/00 ,  G16H20/60 ,  C12Q1/6888 ,  G16H50/30

摘要： Provided herein are methods for altering a health state of a subject by administering a wellness intervention to subjects found to have quantitative measures of microbial genera in the subject's microbiome that are associated with undesirable health states. Undesirable health states can be inferred by executing models that predict health states based on the quantitative measures, such as relative amounts of selected microbial genera to all microbes. Models are created by statistical methods that analyze datasets that include, for each of a plurality of subjects, verified health states and quantitative measures of each of a plurality of microbes classified at designated taxonomic levels, e.g., genus level.