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公开(公告)号:US10125092B2
公开(公告)日:2018-11-13
申请号:US15505282
申请日:2015-09-04
申请人: Rohan Eric John Beckwith , Luis Brito , Brian Addison Dechristopher , Gabriel Grant Gamber , Andrew Geall , Thomas Zabawa
发明人: Rohan Eric John Beckwith , Luis Brito , Brian Addison Dechristopher , Gabriel Grant Gamber , Andrew Geall , Thomas Zabawa
IPC分类号: A61K9/127 , A61K48/00 , C12N15/85 , C07K14/535 , C07C219/06 , A61K47/18 , A61K47/22 , A61K9/51 , A61K31/7105 , A61K31/711 , A61K31/713 , C07C229/12 , C07D211/62 , C07C219/16 , C07D211/34 , C07D295/15 , C07C217/58 , C07D207/08
摘要: This invention provides for a compound of formula (I), or a pharmaceutically acceptable salt thereof, wherein RA, RB, R2 and R4 are defined herein. The compounds of formula (I) and pharmaceutically acceptable salts thereof are cationic lipids useful in the delivery of biologically active agents to cells and tissues.