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1.
公开(公告)号:US07169570B2
公开(公告)日:2007-01-30
申请号:US10795157
申请日:2004-03-04
CPC分类号: G01N33/5041 , G01N33/5035 , G01N33/5047
摘要: Disclosed are methods for evaluating the activation of Bcl10 in a cell in response to a putative stimulus, as well as methods for evaluating or identifying a regulatory compound which regulates activation of Bcl10-mediated signal transduction. These methods utilize the discovery of the activation-dependent formation in a cell of Bcl10 aggregates in a cell.
摘要翻译: 公开了用于评估响应于推定的刺激的细胞中Bcl10的活化的方法,以及用于评估或鉴定调节Bcl10介导的信号转导活化的调节化合物的方法。 这些方法利用细胞中Bcl10聚集体的细胞中活化依赖性形成的发现。