公开(公告)号：US06600065B2

公开(公告)日：2003-07-29

申请号：US10272380

申请日：2002-10-17

申请人： Byeong No Lee ,  Eun Joo Jang ,  Hyung Soo Cho ,  Byung Soon Chun

发明人： Byeong No Lee ,  Eun Joo Jang ,  Hyung Soo Cho ,  Byung Soon Chun

IPC分类号： C07C6966

CPC分类号： C07C67/37 ,  C07C69/675

摘要： Disclosed herein is a novel process for preparing 3-hydroxyesters, comprising: (a) reacting an epoxide derivative with carbon monoxide and alcohol in a solvent at a temperature of 30˜150° C. under a pressure of 50˜3000 psig by using a catalyst system consisting of a catalytic amount of a cobalt compound and optionally an effective amount of a promoter to produce a 3-hydroxyester or a derivative thereof; (b) separating the resulting product and the solvent from the cobalt compound and the promoter in a stripping column at a temperature of −30˜200° C. in an atmosphere of a stabilizing gas; and (c) recycling a part or all of the separated cobalt compound and promoter to the step (a) and repeating the steps (a) through (c).

摘要翻译： 本文公开了一种制备3-羟基酯的新方法，其包括：（a）使环氧化物衍生物与一氧化碳和醇在溶剂中在30〜150℃的温度下在50〜3000psig的压力下反应， 催化剂体系由催化量的钴化合物和任选的有效量的助催化剂组成，以产生3-羟基酯或其衍生物; （b）在稳定气体的气氛中，在-30〜200℃的温度下，将得到的产物和溶剂与汽提塔中的钴化合物和助催化剂分离; 和（c）将部分或全部分离的钴化合物和促进剂再循环到步骤（a）并重复步骤（a）至（c）。