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1.
公开(公告)号:US07510854B2
公开(公告)日:2009-03-31
申请号:US11239674
申请日:2005-09-28
申请人: Markus Pompejus , Burkhard Kröger , Hartwig Schröder , Oskar Zelder , Gregor Haberhauer , Jun-Won Kim , Heung Shick-Lee , Byung-Joon Hwang
发明人: Markus Pompejus , Burkhard Kröger , Hartwig Schröder , Oskar Zelder , Gregor Haberhauer , Jun-Won Kim , Heung Shick-Lee , Byung-Joon Hwang
摘要: Isolated nucleic acid molecules, designated MP nucleic acid molecules, which encode novel MP proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MP nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated MP proteins, mutated MP proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of MP genes in this organism.
摘要翻译: 描述了编码来自谷氨酸棒杆菌的新型MP蛋白的分离的核酸分子,称为MP核酸分子。 本发明还提供反义核酸分子,含有MP核酸分子的重组表达载体,以及引入了表达载体的宿主细胞。 本发明还进一步提供分离的MP蛋白,突变的MP蛋白,融合蛋白,抗原肽和用于基于该生物体中MP基因的遗传工程改进谷氨酸棒球菌产生所需化合物的方法。