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公开(公告)号:US20090203747A1
公开(公告)日:2009-08-13
申请号:US11994354
申请日:2006-06-29
申请人: Corinne Chaimbault , Cyrille Drouot , Laure Jamot , Rebecca Pruss , Celine Simon
发明人: Corinne Chaimbault , Cyrille Drouot , Laure Jamot , Rebecca Pruss , Celine Simon
IPC分类号: A61K31/426 , C07D277/38 , C07D401/02 , C07C337/08 , A61K31/437 , A61P25/00
CPC分类号: C07D277/50
摘要: The present invention relates to the field of pharmacy, especially the treatment of neurodegenerative diseases. The invention specifically relates to a family of chemical compounds for which a neuroprotective activity has been demonstrated.Given that certain members of said family are novel compounds which have never been described, the invention relates to said novel products, the synthesis method thereof and certain novel intermediate synthesis products.The present invention further relates to compositions comprising the compounds of said family, and the use of said compounds as medicaments, especially for the preparation of a medicament for the treatment of neurodegenerative diseases.
摘要翻译: 本发明涉及药学领域,特别是治疗神经变性疾病。 本发明具体涉及已经证明了神经保护活性的化合物族。 鉴于所述家族的某些成员是未经描述的新化合物,本发明涉及所述新产品,其合成方法和某些新型中间体合成产品。 本发明还涉及包含所述家族化合物的组合物和所述化合物作为药物的用途,特别是用于制备用于治疗神经变性疾病的药物。