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1.Chemical derivatives as antitelomerase agents which bind specifically to the G-quadruplex DNA structures and their application as a specific anticancer agent 审中-公开
Title translation: 化学衍生物作为特异性结合G-四链体DNA结构的抗端粒酶试剂及其作为特异性抗癌剂的应用公开(公告)号:US20070232572A1
公开(公告)日:2007-10-04
申请号:US10773806
申请日:2004-02-06
Applicant: Augustin Hittinger , Thomas Caulfield , Patrick Mailliet , Herve Bouchard , Eliane Mandine , Jean-Louis Mergny , Lionel Guittat , Jean-Francois Riou , Dennis Gomez , Chafke Belmokhtar
Inventor: Augustin Hittinger , Thomas Caulfield , Patrick Mailliet , Herve Bouchard , Eliane Mandine , Jean-Louis Mergny , Lionel Guittat , Jean-Francois Riou , Dennis Gomez , Chafke Belmokhtar
IPC: A61K31/47 , A61K31/497 , A61K31/56 , A61K31/66 , C07D215/00
CPC classification number: C07D401/14 , C07D215/38
Abstract: The present invention relates to cancer therapy and to novel anticancer agents having a mechanism of action which is quite specific. It also relates to novel chemical compounds and their therapeutic application in humans.
Abstract translation: 本发明涉及癌症治疗和具有非常特异性的作用机制的新型抗癌剂。 它还涉及新型化合物及其在人体中的治疗应用。