公开(公告)号：US20060004321A1

公开(公告)日：2006-01-05

申请号：US11169874

申请日：2005-06-29

Applicant: Tak-Wah Wong ,  Sek-Wen Hui ,  Ching-Hung Chen ,  Chien-Chun Huang ,  Cheng-De Lin

Inventor： Tak-Wah Wong ,  Sek-Wen Hui ,  Ching-Hung Chen ,  Chien-Chun Huang ,  Cheng-De Lin

IPC: A61N1/30

CPC classification number: A61N1/0424 ,  A61N1/044 ,  A61N1/0476 ,  A61N1/327

Abstract: A painless drug delivery electrode device includes a substrate having top and bottom sides, and an electrode unit provided on the top side of the substrate and adapted to convey pulse signals to a skin. The electrode unit includes a plurality of positive and negative electrode pads which are adapted to contact the skin and which are arranged in rows. Each of the positive and negative electrode pads has a skin contact surface area smaller than 1 sq. mm. Each of the positive electrode pads is spaced apart from an adjacent one of the negative electrodes by a distance ranging from 0.2-1 mm.

Abstract translation: 无痛药物递送电极装置包括具有顶侧和底侧的基底和设置在基底的顶侧上并适于将脉冲信号传送至皮肤的电极单元。 电极单元包括多个正极和负极焊盘，其适于接触皮肤并且排列成行。 正极和负极焊盘中的每一个具有小于1平方毫米的皮肤接触表面积。 每个正电极焊盘与相邻的一个负电极间隔开0.2-1mm的距离。

公开(公告)号：US20070016125A1

公开(公告)日：2007-01-18

申请号：US11438893

申请日：2006-05-23

Applicant: Tak-Wah Wong ,  Sek-Wen Hui ,  Ching-Hung Chen ,  Chien-Chun Huang ,  Cheng-De Lin

Inventor： Tak-Wah Wong ,  Sek-Wen Hui ,  Ching-Hung Chen ,  Chien-Chun Huang ,  Cheng-De Lin

IPC: A61N1/30

CPC classification number: A61N1/327 ,  A61N1/0424 ,  A61N1/044 ,  A61N1/0476

Abstract: An electroporating apparatus includes an electroporation electrode device that has a substrate, and an electrode unit provided on the substrate. The electrode unit includes a plurality of positive and negative electrode pads each of which has a skin contact surface area with a width ranging from 0.2 mm to 0.8 mm. Each positive electrode pad is spaced apart from the adjacent negative electrode pad by an electrode spacing of ranging from 0.5 mm to 1.5 mm. The positive and negative electrode pads are needleless. With a decrease in electrode spacing and electrode width, painless electroporation can be achieved when electric pulses of 0.2 ms or less and 150 V or less are applied is to a skin at 10 Hz or less.

Abstract translation: 电穿孔装置包括具有基板的电穿孔电极装置和设置在基板上的电极单元。 电极单元包括多个正极和负极焊盘，每个正极和负极焊盘具有宽度范围为0.2mm至0.8mm的皮肤接触表面积。 每个正电极焊盘与相邻的负极焊盘间距离为0.5mm至1.5mm的电极间距。 正极和负极焊盘是无针的。 随着电极间距和电极宽度的减小，当施加0.2ms以下且150V以下的电脉冲为10Hz以下的皮肤时，可以实现无痛电穿孔。