公开(公告)号：US09243036B2

公开(公告)日：2016-01-26

申请号：US14421428

申请日：2012-08-15

Applicant: Chintamani Atreya ,  Shilpakala Sainath Rao ,  Krishna Mohan V. Ketha

Inventor： Chintamani Atreya ,  Shilpakala Sainath Rao ,  Krishna Mohan V. Ketha

IPC: C07K7/06 ,  C07K7/08 ,  A61K38/00

CPC classification number: C07K7/08 ,  A61K38/00 ,  A61L27/54 ,  A61L29/16 ,  A61L31/16 ,  A61L2300/25 ,  A61L2300/404 ,  C07K7/06 ,  Y02A50/473

Abstract: Isolated synthetic peptides are disclosed that have anti-microbial activity against E. coli and P. aeruginosa. These isolated peptides can be used as anti-viral agents. The use of these peptides to treat infections with E. coli and P. aeruginosa and viruses are disclosed. The disclosed peptides are also of use for treating a biofilm, such as a biofilm on a medical device.

Abstract translation: 公开了对大肠杆菌和铜绿假单胞菌具有抗微生物活性的分离的合成肽。 这些分离的肽可以用作抗病毒剂。 公开了使用这些肽来治疗大肠杆菌和铜绿假单胞菌和病毒的感染。 所公开的肽也可用于治疗生物膜，例如医疗器械上的生物膜。