公开(公告)号：US06271337B1

公开(公告)日：2001-08-07

申请号：US09168661

申请日：1998-10-08

申请人： Roger Lamartine ,  Isabelle Dumazet ,  Philippe Choquard ,  Arnold Marcillac ,  Francis Vocanson ,  Christian Duchamp

发明人： Roger Lamartine ,  Isabelle Dumazet ,  Philippe Choquard ,  Arnold Marcillac ,  Francis Vocanson ,  Christian Duchamp

IPC分类号： C08G6538

CPC分类号： C08G8/12

摘要： A new two-step process for the preparation and industrial manufacture of calixarenes is disclosed. In the first step, linear phenolic oligomers are prepared in a basic medium from an optionally substituted phenol and a formaldehyde source. The reaction mixture is then neutralized or acidified, and cyclization of the oligomers is brought about at higher temperatures in the same reaction medium which is made water free and optionally completed by higher boiling liquids. The process allows a definite control of the cyclic compounds to be synthesized. Furthermore, novel calixarene compounds are disclosed as well as an installation for carrying out the process on a laboratory or industrial scale.

摘要翻译： 公开了一种用于杯芳烃的制备和工业制造的新的两步法。 在第一步中，在任选取代的苯酚和甲醛源的碱性介质中制备线性酚低聚物。 然后将反应混合物中和或酸化，并在相同的反应介质中使低聚物环化，该反应介质是无水的，任选地通过较高沸点的液体完成。该方法允许将环状化合物确定为 此外，公开了新的杯芳烃化合物以及用于在实验室或工业规模上进行该方法的装置。