Concentrating nikkomicin mixtures
    3.
    发明授权
    Concentrating nikkomicin mixtures 失效
    浓缩nikkomicin混合物

    公开(公告)号:US4552954A

    公开(公告)日:1985-11-12

    申请号:US497433

    申请日:1983-05-26

    摘要: A process for concentrating nikkomicins (X) and (Z) from a dilute impure aqueous solution thereof, comprising contacting the solution with a weakly basic ion exchanger and eluting the adsorbed material with an acid thereby to obtain a concentrated mixture of nikkomicin (X) and nikkomicin (Z). The dilute solution being treated can directly be a filtered microbial cultivation liquor or such a liquor can be prepurified by contact with an acid ion exchanger followed by elution with a base. The recovered material is of relatively high purity.

    摘要翻译: 一种从其稀释的不纯的水溶液中浓缩尼克西米菌素(X)和(Z)的方法,包括使该溶液与弱碱性离子交换剂接触并用酸洗脱吸附的材料,从而得到尼克米霉素(X)和 奈克霉素(Z)。 待处理的稀释溶液可以直接作为过滤的微生物培养液,或者可以通过与酸性离子交换剂接触,然后用碱洗脱来将该液体预纯化。 回收的材料具有相对高的纯度。