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公开(公告)号:US07741022B2
公开(公告)日:2010-06-22
申请号:US11654848
申请日:2007-01-18
申请人: Frederick William Porter , Ann Carol Palmenberg , Christiane Wiese , Yury Alexandrovitch Bochkov
发明人: Frederick William Porter , Ann Carol Palmenberg , Christiane Wiese , Yury Alexandrovitch Bochkov
CPC分类号: A61K38/162 , C07K14/005 , C12N2770/32722
摘要: The invention provides a method of inhibiting Ran protein activity in at least one eukaryotic cell or cell-free extract, the method comprising exposing an amino acid sequence comprising at least a portion of EMCV or TMEV leader protein, wherein the amino acid sequence comprises SEQ. ID NO: 14 or SEQ. ID NO: 15, to at least one cell in an amount effective to inhibit Ran activity in the targeted cell and evaluating Ran protein activity in the cell.
摘要翻译: 本发明提供一种抑制至少一种真核细胞或无细胞提取物中的Ran蛋白活性的方法,该方法包括暴露包含至少一部分EMCV或TMEV前导蛋白的氨基酸序列,其中氨基酸序列包含SEQ ID NO: ID NO:14或SEQ。 至少一个细胞,其量有效抑制靶细胞中的Ran活性并评估细胞中的Ran蛋白活性。
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公开(公告)号:US20070243169A1
公开(公告)日:2007-10-18
申请号:US11654848
申请日:2007-01-18
CPC分类号: A61K38/162 , C07K14/005 , C12N2770/32722
摘要: The invention provides a method of inhibiting Ran protein activity in at least one eukaryotic cell or cell-free extract, the method comprising exposing an amino acid sequence comprising at least a portion of EMCV or TMEV leader protein, wherein the amino acid sequence comprises SEQ. ID NO: 14 or SEQ. ID NO: 15, to at least one cell in an amount effective to inhibit Ran activity in the targeted cell and evaluating Ran protein activity in the cell.
摘要翻译: 本发明提供一种抑制至少一种真核细胞或无细胞提取物中的Ran蛋白活性的方法,该方法包括暴露包含至少一部分EMCV或TMEV前导蛋白的氨基酸序列,其中氨基酸序列包含SEQ ID NO: ID NO:14或SEQ。 至少一个细胞,其量有效抑制靶细胞中的Ran活性并评估细胞中的Ran蛋白活性。
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