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公开(公告)号：US07738959B2
公开(公告)日：2010-06-15
申请号：US10260984
申请日：2002-09-30
IPC分类号： A61N1/37
CPC分类号： A61N1/3712 , A61N1/3716
摘要： Undersensing of an evoked response during an automatically initiated search of the stimulation threshold in a stimulation channel of an IMD, e.g., the pacing threshold in a pacing channel of a pacing system, is minimized by repeating the search using the sense amplifier of the stimulation channel configured in bipolar and unipolar sensing configurations. A failure to sense an evoked response in the search in one sensing configuration can be confirmed, and stimulation energy set to a high output, if an evoked response is not sensed in an alternate sensing configuration or refuted if an evoked response is sensed in the alternate sensing configuration. If the failure is refuted, the alternate sensing configuration is employed until the next search.
摘要翻译： 在IMD的刺激通道中的刺激阈值的自动启动搜索（例如，起搏系统的起搏通道中的起搏阈值）的诱发响应的不足之处通过使用刺激通道的感测放大器重复搜索而被最小化 配置在双极和单极感测配置中。 如果在交替的感测配置中没有感测到诱发的响应，或者如果在交替的感测配置中感测到诱发的响应，则能够将反馈的刺激能量设置为高的输出。 检测配置。 如果故障被驳回，则采用交替感测配置直到下一次搜索。
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公开(公告)号：US07233825B2
公开(公告)日：2007-06-19
申请号：US10367299
申请日：2003-02-15
申请人： David J. Jorgenson , Christopher M. Manrodt , Robert M. Ecker , Lawrence C. McClure , Charles H. Malmskog
发明人： David J. Jorgenson , Christopher M. Manrodt , Robert M. Ecker , Lawrence C. McClure , Charles H. Malmskog
IPC分类号： A61N1/36
CPC分类号： A61N1/3706 , A61N1/3718 , A61N2001/083
摘要： In an implantable medical device having an electrical lead coupled to tissue of a user and a circuit for measuring the impedance of the lead, a method and apparatus for responding to impedance variations in the lead which includes measuring the impedance of the lead while monitoring physiologic parameters of the user, detecting the presence or absence of electromagnetic interference, and if the impedance of the lead is out-of-range, determining whether the electromagnetic interference exceeds a predetermined value, and if the electromagnetic interference exceeds a predetermined value, administering a therapy to the tissue of the user.
摘要翻译： 在具有耦合到用户的组织的电引线和用于测量引线的阻抗的电路的可植入医疗设备中，一种用于响应引线中的阻抗变化的方法和装置，其包括在监测生理参数的同时测量引线的阻抗 检测电磁干扰的存在或不存在，并且如果引线的阻抗超出范围，则确定电磁干扰是否超过预定值，并且如果电磁干扰超过预定值，则施用治疗 到使用者的纸巾。
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公开(公告)号：US07027868B2
公开(公告)日：2006-04-11
申请号：US10004164
申请日：2001-10-30
IPC分类号： A61N1/37
CPC分类号： A61N1/371 , A61N1/3714 , A61N2001/083
摘要： A capture detection algorithm in which atrial capture is detected and distinguished. Further, an immediate measurement of the capture threshold is implemented when a pacemaker switches a lead's polarity from bipolar to unipolar in response to a detected lead failure, in either one or both chambers. Atrial chamber reset (ACR) and AV conduction (AVC), implemented to measure an atrial pacing threshold, are comparatively measured to enable measurement of the atrial pacing threshold. The data that is used to choose between ACR and AVC methods is used to determine the progression of the patient's disease state. Some of the significant aspects of the invention include enablement of accurate threshold measurements, including calculation of stability criteria, precise interval measurements and the use of reference interval to determine capture and loss of capture.
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4.发明授权Clinic based instrument system for remote processing and access to implanted systems information 有权基于诊所的仪器系统，用于远程处理和获取植入系统信息公开(公告)号：US08634926B2
公开(公告)日：2014-01-21
申请号：US10936153
申请日：2004-09-08
IPC分类号： A61N1/372
CPC分类号： A61N1/37282 , A61N1/37247
摘要： A system for accessing implantable medical device (IMD) data is provided including an interrogation appliance to retrieve data from an IMD and transfer the data to a processor. The processor converts the device data to a viewable form that is transferred by the processor to a data destination. The data destination may be an electronic mail address, a secure web site, a facsimile number or the interrogation appliance. The data is presented in a viewable form at the data destination either on a display or by printing. Any number of interrogation appliances may be communicatively coupled to the processor for converting IMD data and providing the IMD data back to a data destination in a viewable form for use by a clinician.
摘要翻译： 提供了一种用于访问植入式医疗设备（IMD）数据的系统，其包括用于从IMD检索数据并将数据传送到处理器的询问设备。 处理器将设备数据转换为由处理器传送到数据目的地的可视窗体。 数据目的地可以是电子邮件地址，安全网站，传真号码或询问设备。 在显示器上或通过打印在数据目的地以可视形式呈现数据。 任何数量的询问设备可以通信地耦合到处理器，用于转换IMD数据，并以可视形式将IMD数据提供给数据目的地，供临床医生使用。
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公开(公告)号：US07280868B2
公开(公告)日：2007-10-09
申请号：US10434689
申请日：2003-05-09
IPC分类号： A61N1/362
CPC分类号： A61N1/368 , A61N1/371 , A61N1/3712 , A61N1/3714 , A61N2001/083
摘要： A capture detection algorithm detects and distinguishes atrial capture. Atrial chamber reset (ACR) and AV conduction (AVC) algorithms are implemented to measure an atrial pacing threshold The data that is used to choose between ACR and AVC methods is used to determine the progression of the patient's disease state. Some of the significant aspects of the invention include enablement of accurate threshold measurements, including calculation of stability criteria, precise interval measurements and the use of reference interval to determine capture and loss of capture.
摘要翻译： 捕获检测算法检测并区分心房捕获。 实施房室复位（ACR）和AV传导（AVC）算法来测量心房起搏阈值用于在ACR和AVC方法之间选择的数据用于确定患者疾病状态的进展。 本发明的一些重要方面包括启用准确的阈值测量，包括稳定性标准的计算，精确的间隔测量以及参考间隔的使用以确定捕获和捕获的丢失。
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公开(公告)号：US06445952B1
公开(公告)日：2002-09-03
申请号：US09573507
申请日：2000-05-18
IPC分类号： A61N108
CPC分类号： A61N1/37 , A61N1/37241 , A61N2001/083
摘要： An apparatus and method for detecting micro-dislodgment at a heart tissue/pacing lead electrode interface involves measuring a first pacing threshold parameter at a first time in a patient's cardiac cycle and measuring a second pacing threshold parameter at a second time in the patient's cardiac cycle. Micro-dislodgment occurring at the heart tissue/pacing lead electrode interface is detected using the first and second pacing threshold parameters. Micro-dislodgment may be detected by comparing a difference between, or a ratio of, the first and second pacing threshold parameters to a preestablished maximum allowable deviation value. A difference between the first and second pacing threshold parameters or a ratio in excess of the preestablished maximum allowable deviation value indicates a problem at the heart tissue/pacing lead interface. The first and second pacing threshold parameters are preferably pacing threshold voltages, and the preestablished maximum allowable deviation value is either a voltage ranging from about 0.2 volts to about 2 volts or a percentage ranging from about 5% to about 100%. The micro-dislodgment procedure may be performed in-situ an implantable pulse generator (IPG), with data indicative of a detected change at the heart tissue/pacing electrode interface being stored in a memory coupled to the IPG and subsequently read out of memory for evaluation. Alternatively, the micro-dislodgment procedure may be performed using an external programmer and may further be performed during implantation of a pacing lead electrode at the heart tissue/pacing lead electrode interface to assure a physician of proper lead attachment.
摘要翻译： 用于检测心脏组织/起搏引线电极界面处的微移位的装置和方法包括在患者的心动周期中第一时间测量第一起搏阈值参数，并在患者的心动周期中第二时间测量第二起搏阈值参数 。 使用第一和第二起搏阈值参数检测在心脏组织/起搏引线电极界面处发生的微移动。 可以通过将第一和第二起搏阈值参数之间的差值或比例与预先建立的最大允许偏差值进行比较来检测微移动。 第一和第二起搏阈值参数之间的差异或超过预先建立的最大允许偏差值的比值表示在心脏组织/起搏引线界面处的问题。 第一和第二起搏阈值参数优选为起搏阈值电压，并且预先建立的最大允许偏差值是约0.2伏特至约2伏范围内的电压或约5％至约100％的百分比。 微移动程序可以原位执行可植入脉冲发生器（IPG），其中指示心脏组织/起搏电极界面上检测到的变化的数据被存储在耦合到IPG的存储器中，随后读出存储器 评估。 或者，可以使用外部编程器执行微移动过程，并且可以在心脏组织/起搏引线电极界面处植入起搏引线电极期间进一步执行微移动过程，以确保医生适当的引线附着。
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