公开(公告)号：US20080152735A1

公开(公告)日：2008-06-26

申请号：US11963628

申请日：2007-12-21

Applicant: Wen-Liang Chang ,  Chen-Wen Yao ,  Ann Chen ,  Chung-Yang Yen ,  Li-Shian Shi ,  Jenn-Han Chen ,  Ching-Len Liao ,  Kuo-Yuan Hwa ,  An-Rong Lee ,  Po-Huang Liang

Inventor： Wen-Liang Chang ,  Chen-Wen Yao ,  Ann Chen ,  Chung-Yang Yen ,  Li-Shian Shi ,  Jenn-Han Chen ,  Ching-Len Liao ,  Kuo-Yuan Hwa ,  An-Rong Lee ,  Po-Huang Liang

IPC: A61K36/236 ,  A61K36/00 ,  A61K36/489 ,  A61K31/352 ,  A61P31/12

CPC classification number: A61K36/484 ,  A61K31/352 ,  A61K36/236 ,  A61K36/489

Abstract: The invention provides a herbal extract having anti-influenza virus activity, by extracting Sophora flavescens Ait, Thesium chinense Turcz, licorice, or mixture thereof with solvent. The herbal extract contains at least one compound selected from the group of compounds represented by following formula (I) or (II) or mixture thereof:

Abstract translation: 本发明提供了具有抗流感病毒活性的草药提取物，通过提取苦参，枸杞，甘草或其与溶剂的混合物。 草药提取物含有至少一种选自由下式（I）或（II）表示的化合物或其混合物的化合物：

公开(公告)号：US20230026646A1

公开(公告)日：2023-01-26

申请号：US17856260

申请日：2022-07-01

Applicant: Chung-Yang YEN

Inventor： Chung-Yang YEN

IPC: G01N33/50 ,  G01N33/68

Abstract: A method for screening a therapeutic drug used for treating psoriasis includes the steps of: (a) isolating and separating fresh peripheral blood mononuclear cells (PBMC); (b) activating the peripheral blood mononuclear cells with a stimulant to cause the cells to produce IFN-γ and RANTES; (c) administering the plurality of candidate drugs to the activated peripheral blood mononuclear cells; (d) detecting expression levels of IFN-γ and RANTES in the peripheral blood mononuclear cells administered with the plurality of candidate drugs; (e) recognizing and removing a disqualified drug from the plurality of candidate drugs according to a variation degree of the expression level of RANTES; and (f) screening the therapeutic drug from the plurality of the candidate drugs excluding the disqualified drug according to the expression level of IFN-γ.

公开(公告)号：US20070154897A1

公开(公告)日：2007-07-05

申请号：US11407101

申请日：2006-04-20

Applicant: Chung-Yang Yen ,  Ching-Len Liao ,  Jenn-Han Chen ,  Wen-Liang Chang ,  Ann Chen ,  Kuo-Yuan Hwa ,  Chen-Wen Yao ,  Chao-Wen Cheng ,  Shun-Min Yang

Inventor： Chung-Yang Yen ,  Ching-Len Liao ,  Jenn-Han Chen ,  Wen-Liang Chang ,  Ann Chen ,  Kuo-Yuan Hwa ,  Chen-Wen Yao ,  Chao-Wen Cheng ,  Shun-Min Yang

IPC: C12Q1/68 ,  G01N33/53 ,  C07H21/04

CPC classification number: G01N33/6893 ,  G01N2800/347

Abstract: The present invention provides biomarkers for detecting kidney disease, selected from the oligonucleotide sequence, complementary sequence or derivatives, amino acid sequence or derivatives, fragment, variants, antibody of annexin A2 or S100A6 or combinations thereof. Moreover, the present invention also provides an assay kit and a method for kidney disease detecting, practically for the kidney disease resulting from acute tubular necrosis.

Abstract translation: 本发明提供了用于检测肾病的生物标志物，其选自寡核苷酸序列，互补序列或衍生物，氨基酸序列或衍生物，片段，变体，膜联蛋白A2或S100A6的抗体或其组合。 此外，本发明还提供了用于肾脏疾病检测的测定试剂盒和方法，实际上用于由急性肾小管坏死引起的肾脏疾病。

公开(公告)号：US20070254290A1

公开(公告)日：2007-11-01

申请号：US11594153

申请日：2006-11-08

Applicant: Chung-Yang Yen ,  Ann Chen ,  Ching-Len Liao ,  Jenn-Han Chen ,  Wen-Liang Chang ,  Chen-Wen Yao ,  Kuo-Yuan Hwa

Inventor： Chung-Yang Yen ,  Ann Chen ,  Ching-Len Liao ,  Jenn-Han Chen ,  Wen-Liang Chang ,  Chen-Wen Yao ,  Kuo-Yuan Hwa

IPC: C12Q1/68

CPC classification number: C12Q1/6883 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/158

Abstract: This invention discloses a method for diagnosing Crescentic glomerulonephritis (CRGN) using at least a sample from a patient. The method is to find a least one biomarker for diagnosing Crescentic glomerulonephritis. The genetic performance of Sparc, Lcn2 and/or Spp1 can be used as biomarkers.

Abstract translation: 本发明公开了一种使用来自患者的至少一个样本来诊断月球性肾小球肾炎（CRGN）的方法。 该方法是找到用于诊断月球性肾小球肾炎的至少一种生物标志物。 Sparc，Lcn2和/或Spp1的遗传表现可用作生物标志物。