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公开(公告)号:US4954496A
公开(公告)日:1990-09-04
申请号:US386232
申请日:1989-07-28
IPC分类号: C07D303/26 , A61K31/335 , A61K31/336 , A61K31/535 , A61P9/00 , C07D303/22 , C07D303/34
CPC分类号: C07D303/22 , C07D303/34 , Y10S514/825 , Y10S514/863 , Y10S514/866
摘要: The invention relates to a cyclohexane derivative, useful as an angiogenesis inhibitor, of the formula: ##STR1## wherein R.sup.1 is halomethyl; or arylthiomethyl which may have amino, lower alkoxy or acylamino,R.sup.2 is lower alkoxy,R.sup.3 is ##STR2## or ##STR3## and R.sup.4 is hydrogen, lower alkylcarbamoyl, lower alkylcarbamoyloxy(lower)alkylcarbamoyl, heterocyclic carbonyl or heterocyclic carbamoyl, or salt thereof.