公开(公告)号：US20240285772A1

公开(公告)日：2024-08-29

申请号：US18106242

申请日：2023-02-06

Applicant: University of Rhode Island Board of Trustees ,  Colgate University

Inventor： Fang Wang ,  Jacob M. Goldberg ,  Bradley M. Lipka ,  Daniel S. Honeycutt

IPC: A61K47/54 ,  C07D213/61 ,  C07D213/64 ,  C07D213/68 ,  C07D213/71 ,  C07D213/76 ,  C07D235/24 ,  C07D235/28 ,  C07D237/12 ,  C07D239/30 ,  C07D277/62

CPC classification number: A61K47/545 ,  C07D213/61 ,  C07D213/64 ,  C07D213/68 ,  C07D213/71 ,  C07D213/76 ,  C07D235/24 ,  C07D235/28 ,  C07D237/12 ,  C07D239/30 ,  C07D277/62

Abstract: Disclosed are pnictogen-containing heterocyclic compounds of Formula (I)




Each of R1, the heterocyclic ring H, A+, LG, and X− is defined herein. Also provided are methods of modifying a substrate using such a compound, conjugated biomolecules thus modified, and pharmaceutical compositions containing one of the conjugated biomolecules.