公开(公告)号：US20230035343A1

公开(公告)日：2023-02-02

申请号：US17782059

申请日：2020-12-04

申请人： Shingo MIYAMOTO ,  Daichi URUSHIYAMA ,  Kenichiro HATA

发明人： Shingo MIYAMOTO ,  Daichi URUSHIYAMA ,  Fusanori YOTSUMOTO ,  Kenichiro HATA

IPC分类号： C12Q1/689 ,  C12Q1/6869

摘要： Provided is a method for predicting the onset of chorioamnionitis, which may predict the onset of chorioamnionitis with high sensitivity. The method including obtaining a base sequence data group of a 16S ribosomal RNA gene in a sample from the vagina of a subject; detecting the presence of a bacterium selected from a bacterial group represented by G1 below based on the data group obtained; and associating the sample with the likelihood of onset of chorioamnionitis based on the number of bacterial species detected. The bacterial group G1: Finegoldia magna; Streptococcus anginosus; Aerococcus christensenii; Lactobacillus jensenii; Ureaplasma parvum; Prevotella disiens; Lactobacillus vaginalis; Prevotella buccalis; Dialister micraerophilus; Atopobium vaginae; Prevotella bivia; Prevotella amnii; Anaerococcus lactolytcus; Streptococcus agalactiae; Anaerococcus tetradius; Bacteroides fragilis; Gardnerella vaginalis; Mycoplasma hominis; and Sneathia sanguinegens.