公开(公告)号：US20100074947A1

公开(公告)日：2010-03-25

申请号：US12483477

申请日：2009-06-12

申请人： Adrian Brown ,  Wayne M. Matthews ,  Daniel N. Margetson ,  Stephen Mark McAllister ,  Danielle Genevieve Rebecca Russell

发明人： Adrian Brown ,  Wayne M. Matthews ,  Daniel N. Margetson ,  Stephen Mark McAllister ,  Danielle Genevieve Rebecca Russell

IPC分类号： A61K9/48

CPC分类号： A61K9/4816

摘要： The present invention is directed to novel pharmaceutically acceptable polymeric compositions suitable for melt extrusion and injection moulding of single or multi-component pharmaceutical dosage forms comprising a plurality of drug substance containing sub-units, being capsule compartments and/or solid sub-units comprising a solid matrix of a polymer which contains a drug substance, the sub-units being connected together in the assembled dosage form.

摘要翻译： 本发明涉及适于熔融挤出和注射成型单组分或多组分药物剂型的新型药学上可接受的聚合物组合物，其包含多个含药物物质的子单元，即胶囊隔室和/或固体亚单元，其包含 含有药物的聚合物的固体基质，所述子单元在组装的剂型中连接在一起。

公开(公告)号：US20110117190A1

公开(公告)日：2011-05-19

申请号：US12741596

申请日：2008-11-07

申请人： Adrian Brown ,  Lee J. Gorringe ,  Stephen Mark McAllister ,  Wayne M. Matthews ,  Danielle Genevieve Rebecca Russell

发明人： Adrian Brown ,  Lee J. Gorringe ,  Stephen Mark McAllister ,  Wayne M. Matthews ,  Danielle Genevieve Rebecca Russell

IPC分类号： A61K9/48 ,  A61K9/00 ,  A61K47/38

CPC分类号： A61K9/4816

摘要： The present invention is directed to novel pharmaceutically acceptable polymeric compositions suitable for melt extrusion and injection moulding of single or multi-component pharmaceutical dosage forms comprising a plurality of drug substance containing sub-units, being capsule compartments and/or solid sub-units comprising a solid matrix of a polymer which contains a drug substance, the sub-units being connected together in the assembled dosage form.

摘要翻译： 本发明涉及适于熔融挤出和注射成型单组分或多组分药物剂型的新型药学上可接受的聚合物组合物，其包含多个含药物物质的子单元，即胶囊隔室和/或固体亚单元，其包含 含有药物的聚合物的固体基质，所述子单元在组装的剂型中连接在一起。