公开(公告)号：US06733748B2

公开(公告)日：2004-05-11

申请号：US09999850

申请日：2001-10-25

Applicant: David Elliott Spaner

Inventor： David Elliott Spaner

IPC: A01N6500

CPC classification number: A61K33/40 ,  A61K35/13 ,  A61K41/0019 ,  A61K41/0023 ,  A61K41/0052 ,  A61K2035/124 ,  C12N5/0693 ,  C12N5/0694 ,  C12N2500/02 ,  A61K2300/00

Abstract: Chronic lymphocytic leukemia (CLL) in a patient is treated by administering to the patient oxidatively stressed CLL cells. The CLL cells are oxidatively stressed extracorporeally, e.g. by subjection to oxygen/ozone mixtures, and preferably are simultaneously subjected to other stressors such as UV light. Preferably also, the CLL cells are autologous, and are contained in an aliquot of the patient's blood at the time of subjection to stressing.

Abstract translation: 通过给予患者氧化应激的CLL细胞治疗患者的慢性淋巴细胞性白血病（CLL）。 CLL细胞体外氧化应激，例如， 通过施用于氧/臭氧混合物，并且优选同时经受其它应激源，例如UV光。 优选地，CLL细胞是自体的，并且在施用压力时被包含在患者血液的等分试样中。