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公开(公告)号:US08937077B2
公开(公告)日:2015-01-20
申请号:US13880767
申请日:2011-10-17
申请人: David Joseph Guerin , Jason D. Brubaker , Michelle Martinez , Joon O. Jung , Neville J. Anthony , Mark E. Scott , Carolyn Michele Cammarano , Dawn Marie Mampreian Hoffman , Hyun Chong Woo , Christopher J. Dinsmore , Philip Jones
发明人: David Joseph Guerin , Jason D. Brubaker , Michelle Martinez , Joon O. Jung , Neville J. Anthony , Mark E. Scott , Carolyn Michele Cammarano , Dawn Marie Mampreian Hoffman , Hyun Chong Woo , Christopher J. Dinsmore , Philip Jones
IPC分类号: A01N43/90 , A61K31/519 , C07D487/00 , C07D471/04 , C07D519/00
CPC分类号: C07D471/04 , A61K31/519 , C07D519/00
摘要: The instant invention provides compounds of formula I which are Jak inhibitors, and as such are useful for the treatment of Jak-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.
摘要翻译: 本发明提供了作为Jak抑制剂的式I化合物,因此可用于治疗Jak介导的疾病如类风湿性关节炎,哮喘,COPD和癌症。
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公开(公告)号:US20130225577A1
公开(公告)日:2013-08-29
申请号:US13880767
申请日:2011-10-17
申请人: David Joseph Guerin , Jason D. Brubaker , Michelle Martinez , Joon O. Jung , Neville J. Anthony , Mark E. Scott , Carolyn Michele Cammarano , Dawn Marie Mampreian Hoffman , Hyun Chong Woo , Christopher J. Dinsmore , Philip Jones
发明人: David Joseph Guerin , Jason D. Brubaker , Michelle Martinez , Joon O. Jung , Neville J. Anthony , Mark E. Scott , Carolyn Michele Cammarano , Dawn Marie Mampreian Hoffman , Hyun Chong Woo , Christopher J. Dinsmore , Philip Jones
IPC分类号: C07D471/04
CPC分类号: C07D471/04 , A61K31/519 , C07D519/00
摘要: The instant invention provides compounds of formula I which are Jak inhibitors, and as such are useful for the treatment of Jak-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.
摘要翻译: 本发明提供了作为Jak抑制剂的式I化合物,因此可用于治疗Jak介导的疾病如类风湿性关节炎,哮喘,COPD和癌症。
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