公开(公告)号：US20110093069A1

公开(公告)日：2011-04-21

申请号：US12897498

申请日：2010-10-04

申请人： Alexei Goraltchouk ,  Dennis E. VanEpps ,  Thomas E. Powell

发明人： Alexei Goraltchouk ,  Dennis E. VanEpps ,  Thomas E. Powell

IPC分类号： A61F2/12

CPC分类号： B05D3/107 ,  A61F2/12 ,  A61L27/30 ,  A61L27/56 ,  A61L2400/18

摘要： Implantable prosthesis, components of prosthesis, and methods of making same are provided. The methods generally include the steps of providing an implant shell, applying a curable fluid composition to the shell to form a coating thereon and applying a particulate component to the composition. The composition is a mixture, for example, an emulsion, containing a silicone-based elastomer dispersion and droplets of a suspended leachable agent. After the elastomer is stabilized and cured, the particulate component and leachable agent are removed, resulting in an implantable member having a porous, open-cell surface texture designed to be effective in reducing incidence of capsular formation or contraction.

摘要翻译： 提供可植入假体，假体的组成部分及其制造方法。 所述方法通常包括提供植入物外壳，将可固化流体组合物施加到外壳上以在其上形成涂层的步骤，并将颗粒组分施用于组合物。 组合物是混合物，例如含有硅氧烷基弹性体分散体和悬浮的可浸出试剂的液滴的乳液。 在弹性体稳定和固化之后，除去颗粒组分和可浸出的试剂，得到可植入的构件，其具有设计成有效减少荚膜形成或收缩的发生率的多孔，开放细胞表面结构。