公开(公告)号：US06297378B1

公开(公告)日：2001-10-02

申请号：US09389067

申请日：1999-09-02

申请人： Ram B. Gupta ,  Dennis J. Jakiela ,  Sampath Venimadhavan ,  Russell C. Cappadona ,  Venkatrao K. Pai

发明人： Ram B. Gupta ,  Dennis J. Jakiela ,  Sampath Venimadhavan ,  Russell C. Cappadona ,  Venkatrao K. Pai

IPC分类号： C07D25116

CPC分类号： C07D251/24

摘要： The invention relates to a novel process for making 2-(2-hydroxy-4-alkoxyphenyl)-4,6-bisaryl-1,3,5-triazine and 2-(2,4-dialkoxyphenyl)-4,6-bisaryl-1,3,5-triazine compounds directly from 2-chloro-4,6-bisaryl-1,3,5-triazine compounds with 3-alkoxyphenol, 1,3-dialkoxylbenzene compounds or mixtures thereof. The reaction step to prepare 2-chloro-4,6-bisaryl-1,3,5-triazines from the reaction of cyanuric chloride with substituted aromatic compounds can be combined with the addition reaction of 3-alkoxyphenol or 1,3-dialkoxylbenzene in a two-step, one-pot process. The 2-(2-hydroxyl-4-alkoxyphenyl)-4,6-bisaryl-1,3,5-triazine, and 2-(2,4-dialkoxyphenyl)-4,6-bisaryl-1,3,5-triazine compounds, are useful to stabilize materials against damage by light, heat, and oxygen, and as stabilizers for organic material, or mixtures thereof.

摘要翻译： 本发明涉及制备2-（2-羟基-4-烷氧基苯基）-4,6-二芳基-1,3,5-三嗪和2-（2,4-二烷氧基苯基）-4,6-二芳基 -1,3,5-三嗪化合物直接由2-氯-4,6-二芳基-1,3,5-三嗪化合物与3-烷氧基苯酚，1,3-二烷氧基苯化合物或其混合物组成。 从氰尿酰氯与取代的芳族化合物的反应制备2-氯-4,6-二芳基-1,3,5-三嗪的反应步骤可以与3-烷氧基苯酚或1,3-二烷氧基苯的加成反应 一个两步一锅的过程。 2-（2-羟基-4-烷氧基苯基）-4,6-二芳基-1,3,5-三嗪和2-（2,4-二烷氧基苯基）-4,6-二芳基-1,3,5-三嗪， 三嗪化合物可用于稳定材料以防止光，热和氧的损伤，以及用作有机材料的稳定剂或其混合物。

公开(公告)号：US06486317B1

公开(公告)日：2002-11-26

申请号：US09691502

申请日：2000-10-18

申请人： Ram B. Gupta ,  Dennis J. Jakiela ,  Sampath Venimadhavan ,  Russell C. Cappadona ,  Venkatrao K. Pai

发明人： Ram B. Gupta ,  Dennis J. Jakiela ,  Sampath Venimadhavan ,  Russell C. Cappadona ,  Venkatrao K. Pai

IPC分类号： C07D25124

CPC分类号： C07D251/22 ,  C07D251/20 ,  C07D251/24

摘要： The invention provides new processes for preparing compositions containing at least one triazine compound, including new compounds for use in these processes to form the compositions and the new compositions that are formed.

摘要翻译： 本发明提供了用于制备含有至少一种三嗪化合物的组合物的新方法，包括用于这些方法的新化合物以形成组合物和形成的新组合物。

公开(公告)号：US06239276B1

公开(公告)日：2001-05-29

申请号：US09335885

申请日：1999-06-18

申请人： Ram B. Gupta ,  Dennis J. Jakiela

发明人： Ram B. Gupta ,  Dennis J. Jakiela

IPC分类号： C07D25124

CPC分类号： C07D251/24 ,  C08K5/3492 ,  C09K15/30

摘要： This invention relates generally to para-tertiary alkyl phenyl substituted pyrimidines and triazines and the use thereof to protect against degradation by environmental forces, inclusive of ultraviolet light, actinic radiation, oxidation, moisture, atmospheric pollutants and combinations thereof. The new class of para-tertiary alkyl phenyl substituted pyrimidines and triazines includes two tertiary alkylated phenyl groups, and a resorcinol or substituted resocinol group attached to the triazine or pyrimidine ring. These materials may, under the appropriate circumstances, be bonded to formulations comprising coatings, polymers, resins, organic compounds and the like via reaction of the bondable functionality with the materials of the formulation. A method for stabilizing a material by incorporating such para-tertiary alkyl phenyl substituted pyrimidines and triazines is also disclosed.

摘要翻译： 本发明一般涉及对叔烷基苯基取代的嘧啶和三嗪及其用于防止包括紫外光，光化辐射，氧化，水分，大气污染物及其组合在内的环境力降解的用途。 新类对叔烷基苯基取代的嘧啶和三嗪包括两个叔烷基化苯基，以及与三嗪或嘧啶环连接的间苯二酚或取代的resocinol基团。 这些材料可以在适当的情况下通过可结合的官能团与制剂的材料的反应与包含涂料，聚合物，树脂，有机化合物等的制剂结合。 还公开了通过并入这种对叔烷基苯基取代的嘧啶和三嗪来稳定材料的方法。

公开(公告)号：US06710177B2

公开(公告)日：2004-03-23

申请号：US09779604

申请日：2001-02-09

申请人： Ram B. Gupta ,  Dennis J. Jakiela ,  Sampath Venimadhavan ,  Russell C. Cappadona ,  Venkatrao K. Pai

发明人： Ram B. Gupta ,  Dennis J. Jakiela ,  Sampath Venimadhavan ,  Russell C. Cappadona ,  Venkatrao K. Pai

IPC分类号： C07D25124

CPC分类号： C07D251/24 ,  C07D251/22

摘要： It has been now surprisingly discovered after extensive research that 2-halo-4,6-bisaryl-1,3,5-triazine can be prepared with unprecedented selectivity, efficiency, mild conditions, and in high yield by the reaction of cyanuric halide with aromatics in the presence of at least one Lewis acid and at least one reaction promoter. This reaction is also unprecedently general as a variety of aromatics can be used to produce a wide selection of 2-halo-4,6-bisaryl-1,3,5-triazines. The novel approach includes the use of the reaction promoters in combination with at least one Lewis acid under certain reaction conditions to promote the formation of 2-halo-4,6-bisaryl-1,3,5-triazine compounds from cyanuric halide. Preferably, the Lewis acids and reaction promoters are combined to form a complex. 2-Halo-4,6-bisaryl-1,3,5-triazines are key intermediates for making 2-(2-oxyaryl)-4,6-bisaryl-1,3,5-triazine class of UV absorbers.

摘要翻译： 现在已经广泛研究出人意料地发现，2-卤代-4,6-二芳基-1,3,5-三嗪可以以前所未有的选择性，效率，温和条件制备，并且通过氰尿酰卤与 芳族化合物在至少一种路易斯酸和至少一种反应促进剂的存在下进行。 该反应也是前所未有的，因为各种芳族化合物可用于产生广泛选择的2-卤代-4,6-二芳基-1,3,5-三嗪。 该新方法包括在某些反应条件下使用反应促进剂与至少一种路易斯酸组合以促进由氰尿酰卤形成2-卤代-4,6-二芳基-1,3,5-三嗪化合物。 优选将路易斯酸和反应促进剂组合以形成络合物。 2-卤代-4,6-二芳基-1,3,5-三嗪是制备2-（2-氧芳基）-4,6-双芳基-1,3,5-三嗪类UV吸收剂的关键中间体。

公开(公告)号：US06297377B1

公开(公告)日：2001-10-02

申请号：US09335790

申请日：1999-06-18

申请人： Ram B. Gupta ,  Dennis J. Jakiela ,  Robert G. Fischer

发明人： Ram B. Gupta ,  Dennis J. Jakiela ,  Robert G. Fischer

IPC分类号： C07D25170

CPC分类号： C07D251/24 ,  C08K5/3492

摘要： This invention relates generally to benzocycle-substituted pyrimidines and triazines and the use thereof to protect against degradation by environmental forces, inclusive of ultraviolet light, actinic radiation, oxidation, moisture, atmospheric pollutants and combinations thereof. The new class of benzocycle-substituted pyrimidines and triazines comprises a benzocycle attached to the triazine or pyrimidine ring, and preferably an additional aryl ring containing a hydroxyl group, either free or blocked to form a latent stabilizer, ortho- to the point of attachment to the triazine or pyrimidine ring. These materials may, under the appropriate circumstances, be bonded to formulations comprising coatings, polymers, resins, organic compounds and the like via reaction of the bondable functionality with the materials of the formulation. A method for stabilizing a material by incorporating such benzocycle-substituted pyrimidines and triazines is also disclosed.

摘要翻译： 本发明一般涉及苯并环取代的嘧啶和三嗪及其用于防止包括紫外光，光化辐射，氧化，水分，大气污染物及其组合在内的环境力降解的用途。 新类型的苯并环取代的嘧啶和三嗪包括与三嗪或嘧啶环连接的苯并环，并且优选含有游离或封闭以形成潜稳定剂的羟基的另外的芳环， 三嗪或嘧啶环。 这些材料可以在适当的情况下通过可结合的官能团与制剂的材料的反应与包含涂料，聚合物，树脂，有机化合物等的制剂结合。 还公开了通过掺入这种苯并环取代的嘧啶和三嗪来稳定材料的方法。

公开(公告)号：US06900314B2

公开(公告)日：2005-05-31

申请号：US10835731

申请日：2004-04-30

申请人： Ram B. Gupta ,  Dennis J. Jakiela ,  Sampath Venimadhavan ,  Russell C. Cappadona ,  Venkatrao K. Pai

发明人： Ram B. Gupta ,  Dennis J. Jakiela ,  Sampath Venimadhavan ,  Russell C. Cappadona ,  Venkatrao K. Pai

IPC分类号： C07D251/14 ,  C07B61/00 ,  C07D251/22 ,  C07D251/24

CPC分类号： C07D251/24 ,  C07D251/22

摘要： It has been now surprisingly discovered after extensive research that 2-halo-4,6-bisaryl-1,3,5-triazine can be prepared with unprecedented selectivity, efficiency, mild conditions, and in high yield by the reaction of cyanuric halide with aromatics in the presence of at least one Lewis acid and at least one reaction promoter. This reaction is also unprecedently general as a variety of aromatics can be used to produce a wide selection of 2-halo-4,6-bisaryl-1,3,5-triazines. The novel approach includes the use of the reaction promoters in combination with at least one Lewis acid under certain reaction conditions to promote the formation of 2-halo-4,6-bisaryl-1,3,5-triazine compounds from cyanuric halide. Preferably, the Lewis acids and reaction promoters are combined to form a complex. 2-Halo-4,6-bisaryl-1,3,5-triazines are key intermediates for making 2-(2-oxyaryl)-4,6-bisaryl-1,3,5-triazine class of UV absorbers.

摘要翻译： 现在已经广泛研究出人意料地发现，2-卤代-4,6-二芳基-1,3,5-三嗪可以以前所未有的选择性，效率，温和条件制备，并且通过氰尿酰卤与 芳族化合物在至少一种路易斯酸和至少一种反应促进剂的存在下进行。 该反应也是前所未有的，因为各种芳族化合物可用于产生广泛选择的2-卤代-4,6-二芳基-1,3,5-三嗪。 该新方法包括在某些反应条件下使用反应促进剂与至少一种路易斯酸组合以促进由氰尿酰卤形成2-卤代-4,6-二芳基-1,3,5-三嗪化合物。 优选将路易斯酸和反应促进剂组合以形成络合物。 2-卤代-4,6-二芳基-1,3,5-三嗪是制备2-（2-氧芳基）-4,6-双芳基-1,3,5-三嗪类UV吸收剂的关键中间体。

公开(公告)号：US06730785B2

公开(公告)日：2004-05-04

申请号：US09779597

申请日：2001-02-09

申请人： Ram B. Gupta ,  Dennis J. Jakiela ,  Sampath Venimadhavan ,  Russell C. Cappadona ,  Venkatrao K. Pai

发明人： Ram B. Gupta ,  Dennis J. Jakiela ,  Sampath Venimadhavan ,  Russell C. Cappadona ,  Venkatrao K. Pai

IPC分类号： C07D25124

CPC分类号： C07D251/24 ,  C07D251/22

摘要： It has been now surprisingly discovered after extensive research that 2-halo-4,6-bisaryl-1,3,5-triazine can be prepared with unprecedented selectivity, efficiency, mild conditions, and in high yield by the reaction of cyanuric halide with aromatics in the presence of at least one Lewis acid and at least one reaction promoter. This reaction is also unprecedently general as a variety of aromatics can be used to produce a wide selection of 2-halo-4,6-bisaryl-1,3,5-triazines. The novel approach includes the use of the reaction promoters in combination with at least one Lewis acid under certain reaction conditions to promote the formation of 2-halo-4,6-bisaryl-1,3,5-triazine compounds from cyanuric halide. Preferably, the Lewis acids and reaction promoters are combined to form a complex. 2-Halo-4,6-bisaryl-1,3,5-triazines are key intermediates for making 2-(2-oxyaryl)-4,6-bisaryl-1,3,5-triazine class of UV absorbers.

公开(公告)号：US06225468B1

公开(公告)日：2001-05-01

申请号：US09388644

申请日：1999-09-02

申请人： Ram B. Gupta ,  Dennis J. Jakiela ,  Sampath Venimadhavan ,  Russell C. Cappadona ,  Venkatrao K. Pai

发明人： Ram B. Gupta ,  Dennis J. Jakiela ,  Sampath Venimadhavan ,  Russell C. Cappadona ,  Venkatrao K. Pai

IPC分类号： C07D25124

CPC分类号： C07D251/24

摘要： Provided is a new process for the preparation of compositions containing at least one triazine ultraviolet light absorber.

摘要翻译： 提供了用于制备含有至少一种三嗪紫外光吸收剂的组合物的新方法。

公开(公告)号：US07485723B2

公开(公告)日：2009-02-03

申请号：US11531932

申请日：2006-09-14

申请人： Ram B. Gupta ,  Dennis J Jakiela ,  Sampath Venimadhavan ,  Russell C Cappadona ,  Venkatrao K. Pai

发明人： Ram B. Gupta ,  Dennis J Jakiela ,  Sampath Venimadhavan ,  Russell C Cappadona ,  Venkatrao K. Pai

IPC分类号： C07D251/24

CPC分类号： C07D251/24 ,  C07D251/22

摘要： It has been now surprisingly discovered after extensive research that 2-halo-4,6-bisaryl-1,3,5-triazine can be prepared with unprecedented selectivity, efficiency, mild conditions, and in high yield by the reaction of cyanuric halide with aromatics in the presence of at least one Lewis acid and at least one reaction promoter. This reaction is also unprecedently general as a variety of aromatics can be used to produce a wide selection of 2-halo-4,6-bisaryl-1,3,5-triazines. The novel approach includes the use of the reaction promoters in combination with at least one Lewis acid under certain reaction conditions to promote the formation of 2-halo-4,6-bisaryl-1,3,5-triazine compounds from cyanuric halide. Preferably, the Lewis acids and reaction promoters are combined to form a complex 2-Halo-4,6-bisaryl-1,3,5-triazines are key intermediates for making 2-(2-oxyaryl)-4,6-bisaryl-1,3,5-triazine class of UV absorbers.

摘要翻译： 现在已经广泛研究出人意料地发现，2-卤代-4,6-二芳基-1,3,5-三嗪可以以前所未有的选择性，效率，温和条件制备，并且通过氰尿酰卤与 芳族化合物在至少一种路易斯酸和至少一种反应促进剂的存在下进行。 该反应也是前所未有的，因为各种芳族化合物可用于产生广泛选择的2-卤代-4,6-二芳基-1,3,5-三嗪。 该新方法包括在某些反应条件下使用反应促进剂与至少一种路易斯酸组合以促进由氰尿酰卤形成2-卤代-4,6-二芳基-1,3,5-三嗪化合物。 优选地，将路易斯酸和反应促进剂组合以形成络合物2-卤代-4,6-二芳基-1,3,5-三嗪是制备2-（2-氧芳基）-4,6-二芳基-1,3,5-三嗪的关键中间体， 1,3,5-三嗪类紫外线吸收剂。

公开(公告)号：US06509399B2

公开(公告)日：2003-01-21

申请号：US09859644

申请日：2001-05-18

申请人： Ram B. Gupta ,  Dennis J. Jakiela

发明人： Ram B. Gupta ,  Dennis J. Jakiela

IPC分类号： C08K53455

CPC分类号： C07D251/24 ,  C08K5/3492 ,  C09K15/30

摘要： This invention relates generally to para-tertiary alkyl phenyl substituted pyrimidines and triazines and the use thereof to protect against degradation by environmental forces, inclusive of ultraviolet light, actinic radiation, oxidation, moisture, atmospheric pollutants and combinations thereof. The new class of para-tertiary alkyl phenyl substituted pyrimidines and triazines includes two tertiary alkylated phenyl groups, and a resorcinol or substituted resocinol group attached to the triazine or pyrimidine ring. These materials may, under the appropriate circumstances, be bonded to formulations comprising coatings, polymers, resins, organic compounds and the like via reaction of the bondable functionality with the materials of the formulation. A method for stabilizing a material by incorporating such para-tertiary alkyl phenyl substituted pyrimidines and triazines is also disclosed.