公开(公告)号：US20170081679A1

公开(公告)日：2017-03-23

申请号：US15265291

申请日：2016-09-14

申请人： Jie Xu ,  Yuqing Chen ,  Jifeng Zhang ,  Dongshan Yang ,  Jun Song

发明人： Jie Xu ,  Yuqing Chen ,  Jifeng Zhang ,  Dongshan Yang ,  Jun Song

IPC分类号： C12N15/90 ,  A61K38/17 ,  A01K67/027 ,  C12N15/89 ,  C12N13/00

CPC分类号： C12N15/907 ,  A01K67/0278 ,  A01K2207/15 ,  A01K2227/107 ,  A01K2267/0306 ,  A61K38/1709 ,  C12N15/89

摘要： The present invention relates to methods and compositions for improving nuclease mediated homologous recombination (HR). The invention is directly relevant to basic biomedical research, transgenic animal production, regenerative medicine, gene therapy, and other disciplines where HR is involved.