Antisense antiviral agent and method for treating ssRNA viral infection
    1.
    发明申请
    Antisense antiviral agent and method for treating ssRNA viral infection 失效
    反义抗病毒药物和治疗ssRNA病毒感染的方法

    公开(公告)号:US20070265214A1

    公开(公告)日:2007-11-15

    申请号:US11431968

    申请日:2006-05-10

    IPC分类号: A61K31/675

    CPC分类号: A61K31/675

    摘要: The invention provides antisense antiviral compounds and methods of their use in inhibition of growth of viruses of the picornavirus, calicivirus, togavirus and flavivirus families, as in treatment of a viral infection. The antisense antiviral compounds have morpholino subunits linked by uncharged phosphorodiamidate linkages interspersed with cationic phosphorodiamidate linkages.

    摘要翻译: 本发明提供反义抗病毒化合物及其用于抑制微小核糖核酸病毒,杯状病毒,披膜病毒和黄病毒家族病毒生长的方法,如治疗病毒感染。 反义抗病毒化合物具有通过分散有阳离子磷酰二胺键的不带电的磷酰二胺键连接的吗啉亚基。