Detection method for monitoring &bgr; tubulin isotype specific modification
    1.
    发明授权
    Detection method for monitoring &bgr; tubulin isotype specific modification 失效
    检测β微管蛋白同种型特异性修饰的检测方法

    公开(公告)号:US06306615B1

    公开(公告)日:2001-10-23

    申请号:US09377554

    申请日:1999-08-19

    IPC分类号: C12Q100

    CPC分类号: G01N33/68 C07K16/18

    摘要: This invention relates to monoclonal antibodies that recognize modified &bgr;-tubulin isotypes, methods of using such antibodies to detect modified &bgr;-tubulin isotypes, methods of using such antibodies to monitor &bgr;-tubulin modifying agents administered to a patient, methods of using such antibodies to isolate modified &bgr;-tubulin, and methods of detecting the anti-modified &bgr;-tubulin antibodies.

    摘要翻译: 本发明涉及识别修饰的β-微管蛋白同种型的单克隆抗体,使用这种抗体以检测修饰的β-微管蛋白同种型的方法,使用此类抗体监测给予患者的β-微管蛋白调节剂的方法,使用这种抗体的方法 分离修饰的β-微管蛋白,以及检测抗修饰β-微管蛋白抗体的方法。