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公开(公告)号：US20050113431A1
公开(公告)日：2005-05-26
申请号：US11012041
申请日：2004-12-14
Applicant: David Brooks , Giora Feuerstein , Eliot Ohlstein , Robert Ruffolo
Inventor： David Brooks , Giora Feuerstein , Eliot Ohlstein , Robert Ruffolo
IPC: A61K31/415 , A61K31/4178 , A61K31/4184
CPC classification number: A61K31/415 , A61K31/4178
Abstract: This invention relates to the use of eprosartan to treat isolated systolic hypertension.
Abstract translation: 本发明涉及依普罗沙坦治疗孤立性收缩期高血压的用途。
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公开(公告)号：US20120035118A1
公开(公告)日：2012-02-09
申请号：US13196068
申请日：2011-08-02
Applicant: Stephen Caltabiano , Eliot Ohlstein , Stewart McCallum
Inventor： Stephen Caltabiano , Eliot Ohlstein , Stewart McCallum
IPC: A61K31/216 , A61K31/7024 , A61P13/00 , A61K31/196
CPC classification number: A61K31/137 , A61K31/216 , A61K45/06 , A61K2300/00
Abstract: Pharmaceutical combinations comprising a beta-3 adrenergic receptor agonist and a muscarinic receptor antagonist, and methods for their use are disclosed. Disclosed combinations include solabegron and oxybutynin. Methods of using the pharmaceutical combinations for the treatment of one or more symptoms associated with overactive bladder, for example, frequency of urgency, nocturia, and urinary incontinence, are also disclosed.
Abstract translation: 公开了包含β-3肾上腺素能受体激动剂和毒蕈碱受体拮抗剂的药物组合及其使用方法。 公开的组合包括溶胶酶和奥昔布宁。 还公开了使用药物组合治疗与膀胱过度活动相关的一种或多种症状的方法，例如紧急频率，夜尿症和尿失禁。
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公开(公告)号：US20070129415A1
公开(公告)日：2007-06-07
申请号：US11673605
申请日：2007-02-12
Applicant: David BROOKS , Giora Feuerstein , Eliot Ohlstein , Robert Ruffolo
Inventor： David BROOKS , Giora Feuerstein , Eliot Ohlstein , Robert Ruffolo
IPC: A61K31/4178
CPC classification number: A61K31/415 , A61K31/4178
Abstract: This invention relates to the use of eprosartan to treat isolated systolic hypertension.
Abstract translation: 本发明涉及依普罗沙坦治疗孤立性收缩期高血压的用途。
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4.发明授权Pharmaceutical combinations of beta-3 adrenergic receptor agonists and muscarinic receptor antagonists 有权β-3肾上腺素能受体激动剂和毒蕈碱受体拮抗剂的药物组合公开(公告)号：US08642661B2
公开(公告)日：2014-02-04
申请号：US13196068
申请日：2011-08-02
Applicant: Stephen Caltabiano , Eliot Ohlstein , Stewart McCallum
Inventor： Stephen Caltabiano , Eliot Ohlstein , Stewart McCallum
CPC classification number: A61K31/137 , A61K31/216 , A61K45/06 , A61K2300/00
Abstract: Pharmaceutical combinations comprising a beta-3 adrenergic receptor agonist and a muscarinic receptor antagonist, and methods for their use are disclosed. Disclosed combinations include solabegron and oxybutynin. Methods of using the pharmaceutical combinations for the treatment of one or more symptoms associated with overactive bladder, for example, frequency of urgency, nocturia, and urinary incontinence, are also disclosed.
Abstract translation: 公开了包含β-3肾上腺素能受体激动剂和毒蕈碱受体拮抗剂的药物组合及其使用方法。 公开的组合包括溶胶酶和奥昔布宁。 还公开了使用药物组合治疗与膀胱过度活动相关的一种或多种症状的方法，例如紧急频率，夜尿症和尿失禁。
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