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公开(公告)号:US20110189186A1
公开(公告)日:2011-08-04
申请号:US13061471
申请日:2009-08-17
申请人: Xu Feng , Zhenqi Shi , Erin McCoy
发明人: Xu Feng , Zhenqi Shi , Erin McCoy
IPC分类号: A61K39/395 , G01N33/569 , A61P35/04 , A61P19/08 , A61P19/10
CPC分类号: C07K16/2896 , A61K2039/505 , G01N33/57415 , G01N2333/70596 , G01N2500/10 , G01N2800/56
摘要: Methods of treating, reducing, and/or preventing cancer metastasis to bone using CD68 blocking agents are provided. For example, the methods can be used to reduce breast cancer metastasis to bone. Also provided are methods of treating, reducing, and/or preventing bone resorption in a subject using CD68 blocking agents. For example, the methods can be used to treat osteoporosis.
摘要翻译: 提供了使用CD68封闭剂治疗,减少和/或预防癌转移至骨的方法。 例如,该方法可用于减少乳腺癌转移至骨骼。 还提供了使用CD68封闭剂治疗,减少和/或预防受试者骨吸收的方法。 例如,该方法可用于治疗骨质疏松症。