公开(公告)号：US20060264608A1

公开(公告)日：2006-11-23

申请号：US11375795

申请日：2006-03-14

申请人： Paul Wender ,  Christopher VanDeusen ,  Kanaka Pattabiraman ,  Erin Pelkey ,  Theodore Jessop

发明人： Paul Wender ,  Christopher VanDeusen ,  Kanaka Pattabiraman ,  Erin Pelkey ,  Theodore Jessop

IPC分类号： C07K7/08 ,  C07K7/06

CPC分类号： C07C271/22 ,  C07C277/08 ,  C07C279/10 ,  C07K1/006

摘要： Synthesis routes that can be adapted to large scale synthesis of oligoguanidine compounds such as oligoarginine compounds are described which use a perguanidinylation step to convert a group of ω-amino groups to the corresponding guanidinyl groups. These compounds find utility as transport agents. Modified oligoguanidine compounds are also described.