-
公开(公告)号:US4724145A
公开(公告)日:1988-02-09
申请号:US798775
申请日:1985-11-18
申请人: Peter K. Murray , Balbir S. Bhogal , Ethel B. Jacobson , Mark S. Crane , Dennis M. Schmatz , Stefan Galuska
发明人: Peter K. Murray , Balbir S. Bhogal , Ethel B. Jacobson , Mark S. Crane , Dennis M. Schmatz , Stefan Galuska
IPC分类号: A61K39/00 , A61K39/012 , C07K14/455 , A61K39/002
CPC分类号: C07K14/455 , A61K39/012 , A61K39/00 , Y10S435/803 , Y10S435/947 , Y10S530/822
摘要: High levels of immunity are achieved in chickens inoculated intramuscularly or orally with E. acervulina extract immunogens. These extracts contain at least 20 polypeptides which induce a protective immune response not only against E. acervulina but also against E. tenella and E. maxima. The resulting immunity prevents intestinal lesions and reduces the number of viable oocysts in vaccinated and challenged birds. One or more of these polypeptides can be used as an immunogen to protect against coccidiosis.
摘要翻译: 通过肌内或口服E.acervulina提取物免疫原接种的鸡获得高水平的免疫。 这些提取物含有至少20种多肽,它们不仅能针对艾美菌(E.acervulina)而且还能针对E. tenella和E.gala 所产生的免疫力可防止肠道病变,并减少接种疫苗和攻击型鸟类的活卵囊数。 这些多肽中的一种或多种可以用作免疫原以防止球虫病。