公开(公告)号：US08524281B2

公开(公告)日：2013-09-03

申请号：US12940797

申请日：2010-11-05

申请人： Sripriya Venkata Ramana Rao ,  Syed Muzafar Shah ,  Christopher Richard Diorio ,  Maja Vencl-Joncic ,  Eugene James Murphy

发明人： Sripriya Venkata Ramana Rao ,  Syed Muzafar Shah ,  Christopher Richard Diorio ,  Maja Vencl-Joncic ,  Eugene James Murphy

IPC分类号： A61K31/4709 ,  A61K35/00

CPC分类号： A61K9/5073 ,  A61K9/5026 ,  A61K31/4709

摘要： The present invention provides an oral pharmaceutical formulation comprising coated spheroids of a kinase inhibitor such as neratinib, which formulation is designed to reduce or eliminate side effects associated with existing oral formulations of kinase inhibitors.