公开(公告)号：US20060160214A1

公开(公告)日：2006-07-20

申请号：US11273164

申请日：2005-11-14

申请人： Koichi Masuda ,  Howard An ,  Eugene Thonar

发明人： Koichi Masuda ,  Howard An ,  Eugene Thonar

IPC分类号： C12N5/08

CPC分类号： C12N5/0655 ,  A61F2002/4445 ,  A61F2002/445 ,  A61K31/728 ,  A61K35/32 ,  A61K38/1709 ,  A61K38/39 ,  C12N2501/155 ,  A61K2300/00

摘要： Surgically implantable tissue engineered intervertebral disc tissues that effectively replicate the physicochemical properties of the corresponding in vivo tissues are provided. Methods for producing such tissues can involve culturing the intervertebral disc cells to produce cells surrounded by an extracellular matrix and culturing the cells and matrix on a semipermeable membrane to form a cohesive tissue.