公开(公告)号：US07691390B2

公开(公告)日：2010-04-06

申请号：US11857961

申请日：2007-09-19

Applicant: Fang-Jen Lee ,  Chia-Jung Yu ,  Ming-Fu Chang ,  Hong-Nerng Ho

Inventor： Fang-Jen Lee ,  Chia-Jung Yu ,  Ming-Fu Chang ,  Hong-Nerng Ho

IPC: A61K39/215 ,  A61K39/00 ,  A61K38/00 ,  A61K39/38 ,  A61K39/12

CPC classification number: C07K14/005 ,  A61K38/00 ,  A61K39/12 ,  A61K39/215 ,  A61K2039/53 ,  C12N2770/20022 ,  C12N2770/20034 ,  G01N2333/165

Abstract: The present invention is directed to an isolated polypeptide containing SEQ ID NO: 1 or an immunogenic fragment thereof. Also disclosed is an isolated nucleic acid encoding the polypeptide or containing a sequence at least 70% identical to SEQ ID NO: 3. Within the scope of this invention are related expression vectors, host cells, and antibodies. Also disclosed are methods of producing the polypeptide, diagnosing coronavirus infection, and identifying a test compound for treating coronavirus infection.

Abstract translation: 本发明涉及含有SEQ ID NO：1或其免疫原性片段的分离的多肽。 还公开了编码多肽的分离的核酸或含有与SEQ ID NO：3至少70％相同的序列。在本发明的范围内，是相关的表达载体，宿主细胞和抗体。 还公开了产生多肽的方法，诊断冠状病毒感染和鉴定用于治疗冠状病毒感染的测试化合物。

公开(公告)号：US20090068636A1

公开(公告)日：2009-03-12

申请号：US11857961

申请日：2007-09-19

Applicant: Fang-Jen Lee ,  Chia-Jung Yu ,  Ming-Fu Chang ,  Hong-Nerng Ho

Inventor： Fang-Jen Lee ,  Chia-Jung Yu ,  Ming-Fu Chang ,  Hong-Nerng Ho

IPC: C12Q1/70

CPC classification number: C07K14/005 ,  A61K38/00 ,  A61K39/12 ,  A61K39/215 ,  A61K2039/53 ,  C12N2770/20022 ,  C12N2770/20034 ,  G01N2333/165

Abstract: The present invention is directed to an isolated polypeptide containing SEQ ID NO: 1 or an immunogenic fragment thereof. Also disclosed is an isolated nucleic acid encoding the polypeptide or containing a sequence at least 70% identical to SEQ ID NO: 3. Within the scope of this invention are related expression vectors, host cells, and antibodies. Also disclosed are methods of producing the polypeptide, diagnosing coronavirus infection, and identifying a test compound for treating coronavirus infection.

Abstract translation: 本发明涉及含有SEQ ID NO：1或其免疫原性片段的分离的多肽。 还公开了编码多肽的分离的核酸或含有与SEQ ID NO：3至少70％相同的序列。在本发明的范围内，是相关的表达载体，宿主细胞和抗体。 还公开了产生多肽的方法，诊断冠状病毒感染和鉴定用于治疗冠状病毒感染的测试化合物。