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1.发明授权Measurement of cytoskeletal proteins and uses thereof in diagnosis, prognosis and therapy 有权细胞骨架蛋白的测定及其在诊断，预后和治疗中的应用公开(公告)号：US09404931B2
公开(公告)日：2016-08-02
申请号：US11608906
申请日：2006-12-11
IPC分类号： G01N33/68
CPC分类号： G01N33/6893
摘要： The present invention relates to monitoring patients for an inflammatory condition or infection (preferably wound infection) by testing an extracellular fluid such as a wound fluid for an elevated level of: (i) vimentin; (ii) a vimentin breakdown product; or (iii) a marker indicative of the presence of vimentin. The present invention provides methods of diagnosis and prognosis, wound dressings, devices (e.g. biosensors) and kits for use in such methods.
摘要翻译： 本发明涉及通过测试诸如伤口液的细胞外液体升高的水平来监测患者的炎症状况或感染（优选伤口感染）：（i）波形蛋白; （ii）波形蛋白分解产物; 或（iii）指示波形蛋白存在的标志物。 本发明提供诊断和预后的方法，伤口敷料，用于这些方法的装置（例如生物传感器）和试剂盒。
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2.发明申请MEASUREMENT OF CYTOSKELETAL PROTEINS AND USES THEREOF IN DIAGNOSIS, PROGNOSIS AND THERAPY 有权细胞因子蛋白质的测定及其在诊断，预防和治疗中的应用公开(公告)号：US20070141131A1
公开(公告)日：2007-06-21
申请号：US11608906
申请日：2006-12-11
申请人： Faraia Shah , Rachael Clark , Partick Trotter , Paul Watt , Breda Cullen
发明人： Faraia Shah , Rachael Clark , Partick Trotter , Paul Watt , Breda Cullen
CPC分类号： G01N33/6893
摘要： The present invention relates to monitoring patients for an inflammatory condition or infection (preferably wound infection) by testing an extracellular fluid such as a wound fluid for an elevated level of: (i) vimentin; (ii) a vimentin breakdown product; or (iii) a marker indicative of the presence of vimentin. The present invention provides methods of diagnosis and prognosis, wound dressings, devices (e.g. biosensors) and kits for use in such methods.
摘要翻译： 本发明涉及通过测试诸如伤口液的细胞外液体升高的水平来监测患者的炎症状况或感染（优选伤口感染）：（i）波形蛋白; （ii）波形蛋白分解产物; 或（iii）指示波形蛋白存在的标志物。 本发明提供诊断和预后的方法，伤口敷料，用于这些方法的装置（例如生物传感器）和试剂盒。
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3.发明授权Diagnosis and prognosis of wound infection by measurement of a phospholipase A2 in wound fluid 有权伤口感染的诊断和预后通过测量伤口液中的磷脂酶A2公开(公告)号：US08685639B2
公开(公告)日：2014-04-01
申请号：US11608940
申请日：2005-06-09
IPC分类号： C12Q1/00
CPC分类号： G01N33/573 , G01N2333/918
摘要： The present invention relates to the diagnosis, prognosis and/or treatment of wound infection by testing wound fluid for the presence of a marker which is present in an amount which is indicative of infection. The marker may be high molecular weight phospholipase A2 (cPLA2) or a marker which is correlated with cPLA2.
摘要翻译： 本发明涉及通过测试伤口液体以存在指示感染量的标记物的存在来诊断，预后和/或治疗伤口感染。 标记物可以是高分子量磷脂酶A2（cPLA2）或与cPLA2相关的标记物。
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4.发明申请DIAGNOSIS AND PROGNOSIS OF WOUND INFECTION BY MEASUREMENT OF A PHOSPHOLIPASE A2 IN WOUND FLUID 有权通过在流体中测量磷脂酶A2来诊断和预防感染公开(公告)号：US20070231380A1
公开(公告)日：2007-10-04
申请号：US11608940
申请日：2006-12-11
申请人： Faraia Shah , Rachael Clark , Patrick Trotter , Paul Watt , Breda Cullen
发明人： Faraia Shah , Rachael Clark , Patrick Trotter , Paul Watt , Breda Cullen
CPC分类号： G01N33/573 , G01N2333/918
摘要： The present invention relates to the diagnosis, prognosis and/or treatment of wound infection by testing wound fluid for the presence of a marker which is present in an amount which is indicative of infection. The marker may be high molecular weight phospholipase A2 (cPLA2) or a marker which is correlated with cPLA2.
摘要翻译： 本发明涉及通过测试伤口液体以存在指示感染量的标记物的存在来诊断，预后和/或治疗伤口感染。 标记物可以是高分子量磷脂酶A 2（cPLA 2 2）或与cPLA 2 N相关的标记物。
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