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1.发明申请SULODEXIDE FOR USE IN THE TREATMENT OF PATHOLOGIES WHEREIN METALLOPROTEINASES ARE INVOLVED 有权用于治疗金属蛋白酶涉及的病理学的SULODEXIDE公开(公告)号：US20130045946A1
公开(公告)日：2013-02-21
申请号：US13642510
申请日：2011-04-20
IPC分类号： A61K31/737 , A61P31/00 , A61P35/00 , C08B37/10 , A61P9/00 , A61P9/10 , C08B37/00 , A61K31/727 , A61P1/04
CPC分类号： A61K31/737 , A61K2300/00
摘要： The present invention describes sulodexide or at least one of its components for use in the reduction of circulating matrix metalloproteinase (MMPs), in particular MMP-9. Sulodexide and its composition are useful for the treatment of pathologies wherein the MMPs are involved, such as cardiovascular disease, cardiovascular disease caused by diabetes, varicose veins, chronic venous insufficiency (CVI), gastrointestinal ulcers, pulmonary disease, and neoplastic pathologies.
摘要翻译： 本发明描述了用于还原循环基质金属蛋白酶（MMP），特别是MMP-9的止痛药或其至少一种成分。 Sulodexide及其组合物可用于治疗其中涉及MMP的病态，例如心血管疾病，由糖尿病引起的心血管疾病，静脉曲张，慢性静脉功能不全（CVI），胃肠溃疡，肺部疾病和肿瘤病变。
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2.发明授权Sulodexide for use in the treatment of pathologies wherein metalloproteinases are involved 有权用于治疗其中涉及金属蛋白酶的病理学的Sulodexide公开(公告)号：US08987231B2
公开(公告)日：2015-03-24
申请号：US13642510
申请日：2011-04-20
IPC分类号： A61K31/727 , A61K31/737
CPC分类号： A61K31/737 , A61K2300/00
摘要： The present invention describes sulodexide or at least one of its components for use in the reduction of circulating matrix metalloproteinase (MMPs), in particular MMP-9. Sulodexide and its composition are useful for the treatment of pathologies wherein the MMPs are involved, such as cardiovascular disease, cardiovascular disease caused by diabetes, varicose veins, chronic venous insufficiency (CVI), gastrointestinal ulcers, pulmonary disease, and neoplastic pathologies.
摘要翻译： 本发明描述了用于还原循环基质金属蛋白酶（MMP），特别是MMP-9的止痛药或其至少一种成分。 Sulodexide及其组合物可用于治疗其中涉及MMP的病态，例如心血管疾病，由糖尿病引起的心血管疾病，静脉曲张，慢性静脉功能不全（CVI），胃肠溃疡，肺部疾病和肿瘤病变。
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