公开(公告)号：US06750208B1

公开(公告)日：2004-06-15

申请号：US09601665

申请日：2000-12-28

申请人： Jean-Claude Yvin ,  Florence Cruz ,  Valérie Descamps ,  Christophe Richard ,  Vesna Thibal ,  Patrick Arrigo ,  Bernard Cloarec

发明人： Jean-Claude Yvin ,  Florence Cruz ,  Valérie Descamps ,  Christophe Richard ,  Vesna Thibal ,  Patrick Arrigo ,  Bernard Cloarec

IPC分类号： A61K31715

CPC分类号： A61K31/702

摘要： The invention concerns a medicine comprising, as active principle, an efficient quantity of at least an oligosaccharide substance capable of modulating apoptosis dysfunction which is capable of modifying apoptosis dysfunctions said substance being selected from the group consisting of oligosaccharides which are derived, by enzymatic or chemical process, from the polymers of the group comprising (1→3)-&bgr;-glucans which optionally comprise (1→6)-&bgr;-branching, and oligosaccharides which are derived, by enzymatic or chemical process, from sulfated galactans, it also concerns a method for treating apoptosis dysfunction.

摘要翻译： 本发明涉及一种药物，其包含有效量的至少一种能够调节凋亡功能障碍的寡糖物质的能力，所述寡糖物质能够修饰凋亡功能障碍，所述物质选自由通过酶促或化学衍生的寡糖 （1-> 6） - 支化的（1-> 3）β-葡聚糖的聚合物和通过酶促或化学方法从硫酸化半乳糖衍生的寡糖， 还涉及治疗凋亡功能障碍的方法。

公开(公告)号：US06387847B1

公开(公告)日：2002-05-14

申请号：US09463065

申请日：2000-01-18

申请人： Jean-Claude Yvin ,  Florence Cruz ,  Jean-Marie Joubert ,  Bernard Cloarec ,  Christophe Richard ,  Bertrand Plesse ,  Marguerite Kopp ,  Bernard Fritig

发明人： Jean-Claude Yvin ,  Florence Cruz ,  Jean-Marie Joubert ,  Bernard Cloarec ,  Christophe Richard ,  Bertrand Plesse ,  Marguerite Kopp ,  Bernard Fritig

IPC分类号： A01N4316

CPC分类号： A01N43/16

摘要： The present invention provides a method to potentiate and stimulate natural defensive reactions of plants to a pathogenic agent. The method comprises application to plants of a composition comprising an effective amount of one or more oligo &bgr; 1-3 glucans composed of 3 to 250 monosaccharide units and a vehicle, wherein the effective amount of oligo &bgr; 1-3 glucans in the composition does not directly stimulate natural defensive reactions of plants when the pathogenic agent is absent.

摘要翻译： 本发明提供了一种加强和刺激植物对病原体的天然防御反应的方法。 该方法包括向植物施用包含有效量的一种或多种由3至250个单糖单元组成的寡聚β1-3葡聚糖和载体的组合物，其中所述组合物中低聚β1-3葡聚糖的有效量不 当病原体不存在时，直接刺激植物的天然防御反应。