Device for delivering a pharmacologically active principle by
electrolytic pumping
    1.
    发明授权
    Device for delivering a pharmacologically active principle by electrolytic pumping 失效
    通过电解泵输送药物活性成分的装置

    公开(公告)号:US5135499A

    公开(公告)日:1992-08-04

    申请号:US659409

    申请日:1991-03-11

    CPC classification number: A61M31/002 F16N11/10 A61M2005/14204

    Abstract: The device includes an electrolysis cell (C) comprising: a closed variable volume first chamber (2) containing an electrolyte that gives off gas under the effect of an electrolysis voltage applied to electrodes (3, 4) in contact with the electrolyte, the gas given off causing the first chamber to expand; and a variable volume second chamber (7) containing the active principle, said second chamber opening out to the outside via an orifice (11) enabling the active principle to be delivered; the total volume of the two chambers (2, 7) being constant, such that expansion of the first chamber causes the volume of the second chamber to be reduced and gives rise to a corresponding controlled expulsion of the active principle contained therein. According to the invention, the two chambers (2, 7) are separated from each other by a flexible wall (6) uniformly subjected to the pressure resulting from gas being given off in such a manner as to reduce the volume of the second chamber (7) and expel the active principle; and the first chamber (2) contains a liquid electrolyte in which the electrodes (3, 4) that extend over the major portion of the length of said first chamber are immersed so that the electrodes are always at least in part in contact with the electrolyte regardless of the position of the device.

    Abstract translation: PCT No.PCT / FR90 / 00526 Sec。 371日期1991年3月11日 102(e)1991年3月11日PCT PCT 1990年7月12日PCT公布。 公开号WO91 / 00753 该装置包括电解槽(C),其包括:封闭的可变体积的第一室(2),其包含在施加到电极(3,4)上的电解电压的作用下释放气体的电解质 与电解液接触,排出的气体使第一室膨胀; 和容纳所述有源原理的可变体积的第二腔室(7),所述第二腔室经由孔口(11)向外打开,从而能够输送活性物质; 两个腔室(2,7)的总体积是恒定的,使得第一腔室的膨胀导致第二腔室的体积减小并且引起其中包含的有效原理的相应的受控排出。 根据本发明,两个腔室(2,7)通过柔性壁(6)彼此分开,柔性壁(6)均匀地受到气体的产生的压力,以减小第二腔室的体积( 7)驱逐有效原则; 并且所述第一腔室(2)包含液体电解质,其中在所述第一腔室的长度的主要部分上延伸的电极(3,4)被浸没,使得电极总是至少部分地与电解质接触 无论设备的位置如何。

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