公开(公告)号：US06411373B1

公开(公告)日：2002-06-25

申请号：US09415389

申请日：1999-10-08

申请人： Jeffrey J. Garside ,  Stephen Monfre ,  Barry C. Elliott ,  Timothy L. Ruchti ,  Glenn Aaron Kees ,  Frank S. Grochocki

发明人： Jeffrey J. Garside ,  Stephen Monfre ,  Barry C. Elliott ,  Timothy L. Ruchti ,  Glenn Aaron Kees ,  Frank S. Grochocki

IPC分类号： G01N3348

CPC分类号： G01N21/474

摘要： The invention provides a design process that is used in the determination of the pattern of detector and illumination optical fibers at the sampling area of a subject. Information about the system, specifically a monochromator (e.g. to determine the optimal number of fibers at an output slit) and the bundle termination at a detector optics stack (e.g. to determine the optimal number of fibers at the bundle termination), is of critical importance to this design. It is those numbers that determine the ratio and number of illumination to detection fibers, significantly limiting and constraining the solution space. Additional information about the estimated signal and noise in the skin is necessary to maximize the signal-to-noise ratio in the wavelength range of interest. Constraining the fibers to a hexagonal perimeter and prescribing a hex-packed pattern, such that alternating columns contain illumination and detection fibers, yields optimal results. In the preferred embodiment of the invention, two detectors share the totality of the detection fibers at the sampling interface. A third group of detection fibers is used for classification purposes.

摘要翻译： 本发明提供了一种设计过程，其用于确定被检体的取样区域处的检测器和照明光纤的图案。 关于系统的信息，特别是单色仪（例如，确定输出狭缝处的光纤的最佳数量）和检测器光学堆叠处的束终止（例如，以确定束终止时的最佳光纤数量）是至关重要的 到这个设计。 这些数字决定了对检测光纤的照射比例和数量，显着限制和限制了解决方案的空间。 关于皮肤估计的信号和噪声的附加信息对于使感兴趣的波长范围内的信噪比最大化是必要的。 将纤维限制在六边形周边，并规定六方填充图案，使得交替的列包含照明和检测纤维，产生最佳结果。 在本发明的优选实施例中，两个检测器在采样接口处共享检测光纤的总体。 第三组检测纤维用于分类目的。