Practical, Cost-Effective Synthesis of Chloromethylated 1, 4-Benzoquinones
    1.
    发明申请
    Practical, Cost-Effective Synthesis of Chloromethylated 1, 4-Benzoquinones 审中-公开
    氯甲基化1,4-苯醌的实用,经济有效的合成

    公开(公告)号:US20080039642A1

    公开(公告)日:2008-02-14

    申请号:US11575749

    申请日:2005-09-17

    IPC分类号: C07C50/28

    CPC分类号: C07C46/00 C07C46/08 C07C50/28

    摘要: The present invention relates to a practical and cost-effective method for the synthesis of 5-chloromethylated 2,3-dialkoxy-6-alkyl-1,4-benzoquinones by direct chloromethylation of the corresponding 2,3-dialkoxy-6-alkyl-1,4-benzoquinones. The invention further relates to a method for the preparation of 5-chloromethylated 2,3-dialkoxy-6-alkyl-1,4-benzoquinones starting from a 3,4,5-trialkoxy-1-alkyl-benzene. The invention also relates to a method for the production of Coenzymes Qn, especially coenzyme Q10.

    摘要翻译: 本发明涉及通过相应的2,3-二烷氧基-6-烷基-1,4-苯醌的直接氯甲基化合成5-氯甲基化2,3-二烷氧基-6-烷基-1,4-苯醌的实用和成本有效的方法。 1,4-苯醌。 本发明还涉及从3,4,5-三烷氧基-1-烷基 - 苯开始制备5-氯甲基化2,3-二烷氧基-6-烷基-1,4-苯醌的方法。 本发明还涉及生产辅酶Q 1,特别是辅酶Q 10的方法。

    Benzamidoxime derivatives, intermediates and processes for their preparation, and their use as fungicides
    5.
    发明授权
    Benzamidoxime derivatives, intermediates and processes for their preparation, and their use as fungicides 失效
    苯甲酰胺肟衍生物,中间体及其制备方法及其作为杀真菌剂的用途

    公开(公告)号:US06680402B2

    公开(公告)日:2004-01-20

    申请号:US10261122

    申请日:2002-10-01

    IPC分类号: C07C25549

    摘要: Benzamidoxime derivatives of the formula I: where R1 is difluoromethyl or trifluoromethyl R2 is hydrogen or fluorine R3 is C1-C4-alkyl which may be substituted by cyano, C1-C4-haloalkyl, C1-C4-alkoxy-C1-C4-alkyl, C3-C6-alkenyl, C3-C6-haloalkenyl, C3-C6-alkynyl, C3-C8-cycloalkyl-C1-C4-alkyl R4 is phenyl-C1-C6-alkyl which may carry one or more substitutents selected from the group consisting of halogen, C1-C4-alkyl, C1-C4-haloalkyl, C1-C4-alkoxy and C1-C4-haloalkoxy on the phenyl ring, or is thienyl-C1-C4-alkyl which may carry one or more substituents selected from the group consisting of halogen, C1-C4-alkyl, C1-C4-haloalkyl, C1-C4-alkoxy and C1-C4-haloalkoxy on the thienyl ring, or is pyrazolyl-C1-C4-alkyl which may carry one or more substituents selected from the group consisting of halogen, C1-C4-alkyl, C1-C4-haloalkyl, C1-C4-alkoxy and C1-C4-haloalkoxy on the pyrazole ring, are prepared, and intermediates for their preparation and their use as fungicides are described.

    摘要翻译: 式I的苯甲酰胺肟衍生物:其中R 1是二氟甲基或三氟甲基R 2是氢或氟,R 3是可以被氰基,C 1 -C 4卤代烷基,C 1 -C 4 - 烷氧基 - C 1 -C 4 - 烷基,C 3 -C 6 - 烯基,C 3 -C 6 - 卤代烯基,C 3 -C 6 - 炔基,C 3 -C 8 - 环烷基-C 1 -C 4 - 烷基R 4是苯基-C 1 -C 6 - 或更多的选自苯基环上的卤素,C 1 -C 4 - 烷基,C 1 -C 4 - 卤代烷基,C 1 -C 4 - 烷氧基和C 1 -C 4 - 卤代烷氧基的取代基,可以携带的噻吩基-C 1 -C 4烷基 一个或多个选自噻吩基环上的卤素,C 1 -C 4 - 烷基,C 1 -C 4 - 卤代烷基,C 1 -C 4 - 烷氧基和C 1 -C 4 - 卤代烷氧基的取代基,其可以是吡唑基-C 1 -C 4烷基, 在吡唑环上携带一个或多个选自卤素,C 1 -C 4 - 烷基,C 1 -C 4 - 卤代烷基,C 1 -C 4 - 烷氧基和C 1 -C 4 - 卤代烷氧基的取代基,制备中间体和 描述了它们作为杀真菌剂的用途。

    Benzamidoxime derivatives, intermediates and processes for their preparation, and their use as fungicides
    7.
    发明授权
    Benzamidoxime derivatives, intermediates and processes for their preparation, and their use as fungicides 失效
    苯甲酰胺肟衍生物,中间体及其制备方法及其作为杀真菌剂的用途

    公开(公告)号:US06509501B2

    公开(公告)日:2003-01-21

    申请号:US10093634

    申请日:2002-03-11

    IPC分类号: C07C25148

    摘要: Benzamidoxime derivatives of the formula I where R1 is difluoromethyl or trifluoromethyl R2 is hydrogen or fluorine R3 is C1-C4-alkyl which may be substituted by cyano, C1-C4-haloalkyl, C1-C4-alkoxy-C1-C4-alkyl, C3-C6-alkenyl, C3-C6-haloalkenyl, C3-C6-alkynyl, C3-C8-cycloalkyl-C1-C4-alkyl R4 is phenyl-C1-C6-alkyl which may carry one or more substitutents selected from the group consisting of halogen, C1-C4-alkyl, C1-C4-haloalkyl, C1-C4-alkoxy and C1-C4-haloalkoxy on the phenyl ring, or is thienyl-C1-C4-alkyl which may carry one or more substituents selected from the group consisting of halogen, C1-C4-alkyl, C1-C4-haloalkyl, C1-C4-alkoxy and C1-C4-haloalkoxy on the thienyl ring, or is pyrazolyl-C1-C4-alkyl which may carry one or more substituents selected from the group consisting of halogen, C1-C4-alkyl, C1-C4-haloalkyl, C1-C4-alkoxy and C1-C4-haloalkoxy on the pyrazole ring, are prepared, and intermediates for their preparation and their use as fungicides are described.

    摘要翻译: 式I的苯甲酰胺肟衍生物,其中R 1是二氟甲基或三氟甲基,R 2是氢或氟,R 3是可被氰基,C 1 -C 4卤代烷基,C 1 -C 4 - 烷氧基-C 1 -C 4 - 烷基,C 3 -C 6 - 烯基 ,C 3 -C 6 - 卤代链烯基,C 3 -C 6 - 炔基,C 3 -C 8 - 环烷基-C 1 -C 4 - 烷基基团R 4是苯基-C 1 -C 6 - 烷基,其可以带有一个或多个选自卤素,C 1 -C 4 - 烷基,C 1 -C 4 - 卤代烷基,C 1 -C 4 - 烷氧基和C 1 -C 4 - 卤代烷氧基,可以带有一个或多个选自卤素,C 1 -C 4 - 在噻吩环上的C 1 -C 4 - 烷基,C 1 -C 4 - 卤代烷基,C 1 -C 4 - 烷氧基和C 1 -C 4 - 卤代烷氧基,可以带有一个或多个选自卤素,C 1 -C 4 - C 1-4 - 烷基,C 1 -C 4 - 卤代烷基,C 1 -C 4 - 烷氧基和C 1 -C 4 - 卤代烷氧基,并且描述了制备中间体及其作为杀真菌剂的用途。

    Benzamidoxim derivatives, intermediate products and methods for preparing and using them as fungicides
    8.
    发明授权
    Benzamidoxim derivatives, intermediate products and methods for preparing and using them as fungicides 失效
    苯甲酰胺衍生物,中间产物和制备和使用它们作为杀真菌剂的方法

    公开(公告)号:US06420605B1

    公开(公告)日:2002-07-16

    申请号:US09508597

    申请日:2000-03-14

    IPC分类号: C07C23304

    摘要: The invention relates to benzamidoxim derivatives of formula (I) wherein the substituents have the following meanings: R1 represents difluoromethyl or trifluoromethyl, R2 represents hydrogen or fluorine, R3 represents C1-C4 alkyl optionally substituted with cyano, C1-C4 halogenalkyl, C1-C4 alkoxy-C1-C4 alkyl, C3-C6 alkenyl, C3-C6 halogenalkenyl, C3-C6 alkinyl, C3-C8 cycloalkyl-C1-C4 alkyl, R4 represents phenyl-C1-C6 alkyl, which can carry one or more substituents selected from the group composed of halogen, C1-C4 alkyl, C1-C4 halogenalkyl, C1-C4 alkoxy or C1-C4 halogenalkoxy on the phenyl ring, or thienyl-C1-C4 alkyl, which can carry one or more substituents selected from the group composed of halogen, C1-C4 alkyl, C1-C4 halogenalkyl, C1-C4 halogenalkoxy on the thienyl ring, or pyrazol-C1-C4 alkyl, which can carry one or more substituents selected from the group composed of halogen, C1-C4 alkyl, C1-C4 halogenalkyl, C1-C4 alkoxy or C1-C4 halogenalkoxy on the pyrazol ring. The invention also relates to intermediate products for the preparation of these derivatives and to their use as fungicides.

    摘要翻译: 本发明涉及式(I)的苯甲酰氨基亚胺衍生物,其中取代基具有以下含义:R 1表示二氟甲基或三氟甲基,R 2表示氢或氟,R 3表示任选被氰基,C 1 -C 4卤代烷基,C 1 -C 4 烷氧基-C 1 -C 4烷基,C 3 -C 6烯基,C 3 -C 6卤代链烯基,C 3 -C 6炔基,C 3 -C 8环烷基-C 1 -C 4烷基,R 4表示苯基-C 1 -C 6烷基,其可以携带一个或多个选自 由苯基环上的卤素,C 1 -C 4烷基,C 1 -C 4卤代烷基,C 1 -C 4烷氧基或C 1 -C 4卤代烷氧基组成的基团,或可以携带一个或多个选自组成的基团的噻吩基-C 1 -C 4烷基 卤素,C 1 -C 4烷基,C 1 -C 4卤代烷基,噻吩基上的C 1 -C 4卤代烷氧基或吡唑基-C 1 -C 4烷基,其可以携带一个或多个选自卤素,C 1 -C 4烷基, 吡唑环上的C 1 -C 4卤代烷基,C 1 -C 4烷氧基或C 1 -C 4卤代烷氧基。 本发明还涉及用于制备这些衍生物的中间产物及其作为杀真菌剂的用途。