公开(公告)号：US20130210670A1

公开(公告)日：2013-08-15

申请号：US13878368

申请日：2011-09-19

申请人： Pierre Miossec ,  Bruno Mougin ,  Malick Paye ,  Frederic Reynier

发明人： Pierre Miossec ,  Bruno Mougin ,  Malick Paye ,  Frederic Reynier

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6883 ,  C12Q2600/106 ,  C12Q2600/158

摘要： Method for determining a level of activity of a biological pathway from a biological sample of a patient suffering from a pathology, the method comprising the steps of: measuring the level of expression of at least three genes from a group of individuals, control individuals or patients, for which the biological pathway is inactive, the at least three genes being associated to the biological pathway, for establishing a negative reference, and measuring level of expression of the at least three genes from a group of individuals, control individuals or patients, for which the biological pathway is active, for establishing a positive reference, and measuring the level of expression of the at least three genes of the patient in the sample.

摘要翻译： 用于确定患有病理学的患者的生物学样品的生物学途径的活性水平的方法，所述方法包括以下步骤：测量来自一组个体，对照个体或患者的至少三种基因的表达水平 ，所述生物学途径不活跃，所述至少三种与生物学途径相关的基因，用于建立负参考，以及测量来自一组个体，对照个体或患者的至少三种基因的表达水平，用于 其生物学途径是活性的，用于建立阳性参考，以及测量样品中患者的至少三种基因的表达水平。